Lecture 6 - Salivary Glands, Stomach and Oesophagus Microanatomy

Question 1

Pathology of Serous fluid secretion?

Answer 1

Ascites

Question 2

Glands and location?

Answer 2

Parotid (ant to ear), submandibular (inf. to jaw), Sublingual (inf to tounge)

Question 3

Mucins function?

Answer 3

Lubrication, limit bacterial adhesion

Question 4

Bicarbonate function?

Answer 4

Counter bacterial secretions, neutralise acid of vomit

Question 5

Lysozyme function?

Answer 5

Breaks down bacterial cell walls

Question 6

Lactoferrin function?

Answer 6

Counters Fe-dependent bacteria

Question 7

IGA function?

Answer 7

Counter bacteria and viruses

Question 8

Amylase function?

Answer 8

Breaks down starches

Question 9

Lipase function?

Answer 9

Breaks down fats and antacids

Question 10

Haptocorrin function?

Answer 10

Binds B12 and protects from gastric acid

Question 11

Dry and mouth and water brash technical terms?

Answer 11

Xerostomia, Hypersalivation

Question 12

Oesophagus wall layers (in to out)?

Answer 12

Epithelium, Lamina Propria, Muscularis Mucosae, Submucosa, Inner circular smooth muscle, Outer longitudinal s.m., Adventitia/Serosa

Question 13

Stomach: Pepsin production?

Answer 13

Chief cells release pepsinogen which is activated into pepsin by the acidic environment created by HCL secreted from parietal cells

Question 14

Pareital cell disfunction?

Answer 14

Decreased acidity of environment, decreasing AA absorption; also decreased food sterilisation leads to less bacteria killing (gastroenteritis)

Question 15

Pernicious anaemia?

Answer 15

Parietal cells releasing insuff. intrinsic factor leads to decreased RBC haematopoesis via B12

Question 16

Simple columnar mucous cell function?

Answer 16

Protective alkaline (HCO3-) mucous coat from acid