Lecture 50 Female Reproductive Function Flashcards
When in a woman’s life is the primary oocyte produced?
Before birth
What is the name of the progenitor cells of the oocytes?l
Oogonia
When in a woman’s life are secondary oocytes produced?
Puberty
Genetically, what is different about oocytes and other gametes
It has double the genetic material 46 chromosomes
What is the additional genetic material in the secondary oocyte held in?
Polar bodies
Name the 2 phases of the ovarian cycle
Follicular phase
Luteal phase
What are primary oocytes stored in?
Follicles (follicular cells)
What cells are the zona pellucida formed by…
Granulosa cells
What is the name of the cavity formed when the primordial follicle enlarges
Antrum
What is the name of the singular follicle which remains after follicular cell enlargement?
Graafin follicle
At the end of the follicular phase, what causes the rupture of the follicle?
Fluid accumulation, releasing the secondary oocyte
What days does the luteal phase occur?
Day 14 - 28 of the ovarian cycle
Corpus haemorrhagicum is what.. and what can it lead to?
The follicle filling with blood
Can lead to irritation and pain.
What is the name of the of the area formed by swelling of theca and granulosa cells, containing fat and blood vessels
Corpus luteum
What hormone is released by the corpus luteum? And what effect does it have
Progesterone
Prevent uterine wall breakdown
What happens when the corpus luteum goes through the preplanned artesia?
There is no more progesterone released, breakdown of the stratum functionalis
Describe the hormonal sequence which leads to the production Of a primordial follicle
Hypothalamus- GnRH - gonadotropin releasing hormone
Anterior pituitary- LH and FSH
Production of an egg
What is the function of luteninizing hormone?
Stimulates ovulation.
What causes the negative feedback which prevents release of GnRH
Corpus luteum, release of progesterone and oestrogen
Name the 2 layers of the uterine wall
Stratum basale- not shed, supplied by basilar arteries
Stratum functionalis- shed away when corpus luteum stops
What is the function of oestrogen?
Thickens walls, and PROLIFERATES-
Name the follicle which is allowed to continue to become a secondary oocyte
Graafin follicle
What forms tubular glands?
Oestrogen
What is found in the tubular glands of the uterus which is beneficial for a potential embryo?
Glycogen
What causes the breakdown of the stratum functionalis
Artesia of the corpus luteum
Leads to ↓ in progesterone
Leads to ischemia and infarction of stratum functionalis (endometrium)
Menstruation
