Lecture 10 Flashcards

1
Q

2 functional units of the liver

A

Lobular arrangement

Liver acinus

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2
Q

Liver acinus arrangement (ZONES)

A

Zone 1 - glycogen and plasma protein production
2
3- detoxification

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3
Q

Functions of Bile

A
  1. Emulsification of fats
  2. Neutralises stomach acid
  3. Excretory channel for bilirubin
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4
Q

2 areas in the liver lobule responsible for blood supply

A
  • portal triad
    Composed of, hepatic artery, bile duct, hepatic portal v
  • central vein
    Takes blood away from the lobule to the IVC
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5
Q

Blood pressure in liver

A

Quite low, but with low resistance, it is possible for this.

- cirrhosis leads to ↑ vascular resistance= low blood supply

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6
Q

Functions of the liver

A

Produce bile
Metabolism of carbs, fats and proteins
Detoxification of toxins

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7
Q

Function of kupffer cells

A

Destroy pathogens and old RBC

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8
Q

Glucose buffer in the liver

A
  • glycogen storage
  • convert galactose and fructose to glucose
  • amino acids —> glucose (gluconeogenesis)
  • fats —> glucose
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9
Q

Fat stores, energy in liver

A

Fatty acids = ketone bodies and ATP (energy)- beta oxidation
Glycerol = glucose

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