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Physiology and Pharmacology > Lecture 4.1 > Flashcards

Lecture 4.1 Flashcards

1
Q

Name three drugs which target ion channels

A

Lignocaine (lidocaine), Apamin, Nifidipine

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2
Q

Name three drugs which target enzymes

A

Captopril, pargyline/clorgyline, acetylsalicylic acid (aspirin)

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3
Q

Name two drugs which target transporters

A

Digoxin, fluoxetine

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4
Q

What is the main function of lignocaine?

A

local anesthetic (sore throat treatment is in strepsils)

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5
Q

What does lignocaine block?

A

Voltage gated Na channels

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6
Q

Where is apamin found in?

A

In bee venom

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7
Q

What is the function of apamin?

A

Causes pain if injected

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8
Q

What does apamin block?

A

K channels which are responsible for hyperpolarization

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9
Q

What group of drugs is nifedipine a part of?

A

Dihydropyridine

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10
Q

What is the function of nifedipine?

A

Used to manage high blood pressure

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11
Q

What does nifidepine block?

A

Calcium channels

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12
Q

What is the function of captopril?

A

Used to treat hypertension

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13
Q

What does captopril inhibit?

A

ACE

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14
Q

What is the function of pargyline/clorgyline?

A

Used as an antidepression

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15
Q

What does pargyline/clorgyline inhibit?

A

Irreversible and selective inhibitor of monoamine oxidase (MAO)

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16
Q

Where is Digoxin derived from?

A

Fox glove

17
Q

What is the function of Digoxin?

A

Used to treat heart conditions e.g. atrial fibrillation

18
Q

What does Digoxin inhibit?

A

Inhibits the Na/K ATPase, lengthening the cardiac action potential

19
Q

What is fluoxetine also known as?

A

Prozac

20
Q

What is the function of fluoxetine?

A

An antidepressant

21
Q

What does fluoxetine inhibit?

A

Selective serotonin reuptake inhibitor

22
Q

What is the function of acetylsalicylic acid?

A

Treatment for pain, fever and inflammation

23
Q

What does acetylsalicylic acid inhibit?

A

Causes irreversible inactivation of cyclooxygenase (COX)

24
Q

What group is acetylsalicylic acid a part of?

A

Type of NSAID

Physiology and Pharmacology (27 decks)

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