Lecture 4 Nutrient Digestion and Absorption Flashcards
Principal dietary constituents
- Carbohydrate
- Protein
- Fat
- Vitamins
- Minerals
- Water
Breakdown products of complex CHO are absorbed where
Small intestine
Lactose
Glucose + galactose
Sucrose
Glucose + fructose
Maltose
Glucose + Glucose
Starch and glycogen glucose molecules are linked via
a-1,4 glycosidic bonds
Where are the a-1,4 glycosidic bonds in starch hydrolysed
In the pancreas by amylase
Cellulose id
Unbranched linear chains of glucose monomers linked by beta 1,4 glycosidic bonds
Membrane domains of epithelial surface
Apical and basal lateral
What are the epithelial cells separated by
Tight junctions
What type of transport occurs across the membrane
Transcellular
Paracellular
Vectorial (needs a minimum of 2 transport proteins)
What is a symporter
a transport protein that transports 2 molecules at a time
What is SGLT1
a symporter
Na binds to symportor which causes a conformational change and
allows glucose to enter the cell
Glucose accumulates in the cell until which point
until the concentration is above 5mmol and then it moves via GLUT2 into the blood
Na enters the blood by
using ATP to pumpNa out of the cell and K into the cell
How does fructose enter the cell
Via Glut5
Di and tripeptides are tranposted into the cell how
Using proton force from hydrogen ions via PepT1
How does H+ bring in Na into the cell
Via NHE3 which creates a acid microclimate