Lecture #4 Flashcards
Osteoclasts?
Breakdown of calcified matrix
Osteoblasts?
Replace cartilage with bone tissue
How does bone tissue maintain homeostasis?
By constant remodeling. The opposing processes of reabsorption and deposition occur on the surfaces of the endosteum in the periosteum
Bone reabsorption?
Removal of bone which is the action of osteoclasts
Bone deposition?
Formation of bone which is the action of osteoblasts
What percent of the skeleton is replaced each year?
10 to 20%
Which factors affect bone development, growth, and repair?
Nutrition, sunlight exposure, hormone levels, and physical exercise
Function of vitamin D on bone formation?
Calcium absorption
The function of vitamin A on bone formation?
Osteoblast and osteoclast activity
Function of vitamin C on bone formation?
Collagen synthesis
Function of growth hormone in skeletal development?
Stimulates cartilage cell division
Function of the thyroid hormone and skeletal development?
Causes replacement of cartilage with bone
Function of the parathyroid hormone on skeletal development?
Stimulates osteoclasts/bone breakdown
What does Somatotropin do?
It is a growth hormone secreted by the anterior pituitary gland
How are fractures classified?
By the cause and the nature of the break
What is a simple or closed fracture?
A fracture protected by uninjured skin or mucous membrane
What is a compound or open fracture?
A fracture in which bone is exposed to the outside through an opening in the skin or mucous membrane
What is a green stick fracture?
An incomplete fracture
What is one way for a green stick fracture to occur?
For it to occur on a convex surface
What is a fissured fracture?
An incomplete longitudinal break
What is a transverse fracture?
A complete brake occurring at a right angle of the axis of the bone
What is an oblique fracture?
Occurs at an angle other than a right angle to the axis of the bone
What is a spiral fracture?
Caused by excess twisting of a bone
What are the four steps in fracture repair?
Hematoma, cartilaginous, bony callus, and remodeling
What is a hematoma?
A pool of mostly clotted blood
What happens during the cartilagineus Callus phase in fracture repair?
Phagocytes remove debris and fibrocartilage invades
What happens during the bony callus phase of a fracture repair?
Osteoblast invade and a hard Callus fills the space
What happens in the remodeling phase of a fracture repair?
Bone is restored close to original shape
What are the major functions of bones?
Provide shape, support, protection, movement, produce red blood cells, and store Inorganic salts
Hematopoiesis?
Blood cell formation
What is a change in bone marrow that can occur with age?
Red bone marrow which produces blood components is replaced with yellow bone marrow which stores fat
What occurs in red bone marrow?
Production of red blood cells, white blood cells, and platelets
What percent of bone matrix consists of inorganic mineral salts?
About 70%
What is the most abundant salt in storage and bone matrix?
Calcium phosphate
What is osteoporosis?
A condition that results from loss of bone mineralization
What are functions of calcium?
Building bones, nerve impulse conduction, and muscle contraction
What is a fragility fracture?
A fracture the occurs from less than standing height which is a sign of low bone density.
What is osteopenia?
Bone density loss. It is what happens before osteoporosis
What happens to the skeletal system as people age?
Decrease in height begins at age 30, calcium levels fall, bones become more brittle, osteoclasts outnumber osteoblasts, vertebral compression fractures