Lecture 3- How We See 2 Flashcards
What is phototransduction
Conversion of light energy to an electrochemical response by the photoreceptors (rods and cones)
What do the phtotransduced rods and cones activate
Optic nerve cells to generate and action potential
Where are the rods and cones located
Deep in the retina
What is more present cones or rods
Rods
What is integrated into the cell membrane of the lamellae that surrounds rods and cones
Visual pigment- Rhodopsin in rods
Opsins in cones
What happen when light rays hit rods
The vitamin A compound reacts to from an isomer (from 11-cis to all trans retinal)
Because it goes from bent to straight it cannot fit and rhodopsin splits and bleaches purple
It then activates a cascade or reaction which closes the sodium channel and leads to hyper polarisation and becomes an action potential directed to the brain
What is Rhodopsin made of
Opsin + 11-cis Retinal
What happens to the remaining trans-retinal
Converted to cis-retinol and used with opsin to reform Rhodopsin
What type of deficiency can affect vision
Vitamin A
Night blindness
Abnormal conjunctiva and corneal epithelium