Lecture 28 - Polycythemias

Question 1

Polycythemia ____ results from a Myeloproliferative neoplasm due to a mutation in Hematopoietic Stem Cell or progenitor cell (specifically in JAK2)–> increase in ALL blood cells.

Answer 1

Polycythemia Vera

Question 2

Secondary Plycythemia results from decreased ____ tension and increase in _____ production.

Answer 2

O2 tension

EPO

Question 3

Relative Polycythemia results from decreased ____ volume (could be caused by dehydration or fluid loss of some kind). The RBC mass is normal, and this disease state can be reversed with return of ____ volume.

Answer 3

Plasma volume

Plasma volume