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MICR221 > Lecture 24 30 days > Flashcards

Lecture 24 30 days Flashcards

1
Q

blocking attachment

A 
vaccine RBP neutralise
I (heat, formaline, main/related)
A (unfavourable, main) 
V (surface antigen, heterologous)
eradicated smallpox
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2
Q

antiviral synthesis drug principle

A

building block analogue (ntide, nside,phosphate) or inhibition
selective host toxicity

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3
Q

entry blocker

A

enfuvirtide (HIV fusion)

amantadine (flu RNA entry endosome)

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4
Q

synthesis blocker

A

acylovir, cidofovir HSV DNA rep

azidothymidine HIV RT
nevirapine non nucleoside analogue HIV bind RT

Ribavirin, Sofosbuvir Hep C RNA rep

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5
Q

assembly blocker

A

polyprotein processing blocker

danoprevir, glecaprevir, simeprevir (Hep C protease, no RdRp cleaved)

Pibrentasvir, Daclatasvir, Velapatasvir (Hep C assembly protein)

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6
Q

release blocker

A

oseltamivir neuraminidase inhibit flu release

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7
Q

mAb vs interferon

A

attachment, dissemination (RSV) palivizumab

innate, dissemination

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MICR221 (22 decks)

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