Lecture 21 Flashcards

1
Q

Small intestine has 3 parts:

A
  1. duodenum
  2. jejunum
  3. ileum
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Histology of the Small Intestine: structures that increase surface area

A
  1. plica circularis
  2. villi
  3. microvilli
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

plica circularis

A
  • permanent ½ inch tall folds that contain part of submucosal layer
  • not found in lower ileum
  • can not stretch
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

villi:

A
  • 1 Millimeter tall
  • Core is lamina propria of mucosal layer
  • Contains vascular capillaries and lacteals
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

microvilli:

A

cell surface feature known as brush border

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Functions of Microvilli:

A
  1. Absorption and digestion
  2. Digestive enzymes found at cell surface on microvilli
  3. Significant cell division within intestinal glands
    proteins
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Roles of Intestinal Juice & Brush-Border Enzymes:

A
  1. Submucosal layer has duodenal glands

2. Mucosal layer contains intestinal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Submucosal layer secretes

A

alkaline mucus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Mucosal layer:

A

Crypts of Lieberkuhn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Crypts of Lieberkuhn :

A
  • secretes intestinal juice
  • brush border enzymes
  • paneth cells secrete lysozyme kills bacteria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Digestion of Carbohydrates:

mouth

A

salivary amylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Digestion of Carbohydrates:Esophagus & stomach—

A

nothing happens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Digestion of Carbohydrates: Duodenum—-

A

pancreatic amylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Digestion of Carbohydrates: brush border enzymes

A

act on disaccharides

  • produces monosaccharides
  • lactose intolerance
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lactose Intolerance:

A

Mucosal cells of small intestine fail to produce lactase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Digestion of Proteins: stomach

A
  1. HCl denatures or unfolds proteins

2. pepsin turns proteins into peptides

17
Q

Digestion of Proteins: pancreas

A
  1. digestive enzymes split peptide bonds between different amino acids
  2. brush border enzymes split off amino acid at amino end of molecule
18
Q

Digestion of Lipids: mouth

A

lingual lipase

19
Q

Digestion of Lipids: small intestine

A
  1. emulsification by bile
  2. pancreatic lipase splits into fatty acids & monoglyceride
  3. no enzymes in brush border
20
Q

Digestion of Nucleic Acids:

A
  1. Pancreatic juice = RNA and DNA
  2. Nucleotides produced are digested by enzymes
  3. absorbed by active transport
21
Q

Absorption of Monosaccharides:

A

into and out of epithelial cell

22
Q

Absorption into epithelial cell

A
  1. glucose & galactose=sodium symporter

2. fructose=facilitated diffusion

23
Q

Movement out of epithelial cell into bloodstream:

A

by facilitated diffusion

24
Q

Absorption of small fatty acids:

A

enter cells & then blood by simple diffusion

25
Q

Absorption of larger lipids:

A

exist only within micelles (bile salts coating)

26
Q

Lipids enter cells by

A

simple diffusion leaving bile salts behind in gut

27
Q

Bile salts reabsorbed into

A

blood & reformed into bile in the liver

28
Q

Inside epithelial cells fats are

A

rebuilt and coated with protein to form chylomicrons

29
Q

Chylomicrons leave intestinal cells by

A

exocytosis into a lacteal

  • travel in lymphatic system
  • removed from the blood by the liver and fat tissue
30
Q

Sources of electrolytes:

A

GI secretions & ingested foods and liquids

31
Q

Enter epithelial cells by

A

diffusion & secondary active transport

32
Q

sodium & potassium move =

A

Na+/K+ pumps (active transport)

33
Q

chloride, iodide and nitrate =

A

passively follow

34
Q

iron, magnesium & phosphate ions =

A

active transport

35
Q

Intestinal Ca+ absorption requires

A

vitamin D & parathyroid hormone

36
Q

Fat-soluble vitamins:

A

travel in micelles & are absorbed by simple diffusion

37
Q

Water-soluble vitamins

A

absorbed by diffusion

38
Q

B12 combines with

A

intrinsic factor before it is transported into the cells

-receptor mediated endocytosis

39
Q

Absorption of Water:

A

by osmosis

9 L each day