Lecture 15 Flashcards
Cells Types of the Alveoli:
Type I alveolar cells
Type II alveolar cells (septal cells)
Alveolar dust cells
Type I alveolar cells:
simple squamous cells where gas exchange occurs
Type II alveolar cells (septal cells):
free surface has microvilli
secrete alveolar fluid containing surfactant
Alveolar dust cells:
wandering macrophages remove debris
Alveolar-Capillary Membrane:
Respiratory membrane = 1/2 micron thick
Exchange of gas from alveoli to blood
4 Layers of membrane to cross
Vast surface area = handball court
4 Layers of membrane to cross:
- alveolar epithelial wall of type I cells
- alveolar epithelial basement membrane
- capillary basement membrane
- endothelial cells of capillary
Breathing or Pulmonary Ventilation:
- Air moves into lungs when pressure inside lungs is less than atmospheric pressure
- Air moves out of the lungs when pressure inside lungs is greater than atmospheric pressure
Boyle’s Law:
- As the size of closed container decreases, pressure inside is increased
- The molecules have less wall area to strike so the pressure on each inch of area increases.
Quiet Inspiration:
- Diaphragm moves 1 cm & ribs lifted by muscles
- Intrathoracic pressure falls and 2-3 liters inhaled
Quiet Expiration:
- Passive process with no muscle action
- Elastic recoil & surface tension in alveoli pulls inward
- Alveolar pressure increases & air is pushed out
Labored Breathing:
Forced expiration and inspiration
Forced expiration:
abdominal mm force diaphragm up
internal intercostals depress ribs
Forced inspiration:
sternocleidomastoid, scalenes & pectoralis minor lift chest upwards as you gasp for air
Summary of Breathing:
- Alveolar pressure decreases & air rushes in
2. Alveolar pressure increases & air rushes out
Alveolar Surface Tension:
Thin layer of fluid in alveoli causes inwardly directed force
-water molecules strongly attach to each other