Lecture 2: Development and Meninges Flashcards
Which part of gastrulation does neurulation occur?
A the later part of gastrulation
What is the Notochord?
A tissue that signals the ectoderm to involute and become the CNS
What signals the Ectoderm to involute?
Protein signals from the Notochord
What is the Neural fold?
The part of the Ectoderm that involutes
What is the Neural Plate?
The part of the ectoderm that involutes and become nervous tissue
What happens after the Ectoderm involutes?
It becomes the neural tube
What does the Neural tube become?
The developing CNS
What does the Neural tube arise from?
The Ectoderm
What does the CNS arise from?
Ectoderm
What does the Neural Crest form?
The entire PNS
Why does the Neural crest form?
Because it does not receive as many signals the cells in the centre
What does the area of the ectoderm that did not receive any signals from the notochord become?
The epidermis
What does the Ectoderm form?
PNS (neural crest), CNS (neural tube) and Epidermis
What does the Somite do?
Signals to the neural crest cells if it is going to become the PNS or another cell type like the cells in the skin
What does the space in the neural tube become?
The ventricles of the brain
What do the Somites do?
They signal for the neural crest cells to become part of the PNS
What does the Neural tube become?
Either the spinal cord or the brain
What kind of cells can the neural crest cells become?
•Unipolar sensory neurons
•Glial cells (Microglial cells, Schwann cells and Satelite Glial cells)
Overall what does the Ectoderm form?
•Neural tube (CNS - Brain and Spinal cord)
•Neural Crest (Sensory neurons and glial cells)
•Epidermis (Skin)
What Glial cells come from the Neural Crest cells?
•Microglial cells
•Schwann cells
•Satellite Glial cells
Where are cell bodies of motor neurons?
In the spinal cord
What do Motor neurons originate from?
The Neural tube because they originate from the CNS
What cells originate from the neural tube?
•Motor neurons
•Cortical neurons
•Oligodendrocytes
•Microglia
•Astrocytes
•Ependymal cells
Which microglial cells originate in the neural tube?
•Oligodendrocytes
•Microglia
•Astrocytes
•Ependymal cells
Which neurons originate from the neural tube?
•Cortical neurons
•Motor neurons
What does each type of glial cell originate from?
Neural Crest
•Microglial
•Satellite
•Schwann
Neural Tube
•Oligodendrocyte
•Schwann
•Microglia?
•Astrocytes
•Ependymal cells
What are the components of Primary Expansion?
•Forebrain
•Midbrain
•Hindbrain
What is the other names for the Forebrain, Midbrain and Hindbrain?
Forebrain - Prosencephalon
Midbrain - Mesencephalon
Hindbrain Rhombencephalon
What does the Forebrain divide into?
The Telencephalon and the Diencephalon
What do the Telencephalon and Diencephalon originate from?
The Forebrain
What does the Midbrain divide into?
It does not divide