Lecture 16: Hypothalamus, Pituitary Gland, and Pineal Gland Flashcards
What is unique about the Hypothalamus, Pituitary Gland and Pineal gland?
All of the structures are midline and there is only one of each
What is the main function of the hypothalamus?
To maintain homeostasis
How does the hypothalamus maintain homeostasis?
By regulating ANS (ascending and descending tract)
What do the ANS ascending and descending tracts regulated by the hypothalamus do?
Control body temperature, hunger, thirst, fatigue, sleep and circadian cycles
What does the hypothalamus link togehter?
The nervous system to the endocrine system
What links the nervous system to the endocrine system?
The hypothalamus
Through what does the hypothalamus link the nervous system to the endocrine system?
Via the pituitary gland
How does the hypothalamus link the nervous and endocrine system via the pituitary gland?
By secreting neurohormones that stimulate or inhibit secretions of the pituitary gland
What does the hypothalamus synthesize and secrete?
Neurohormones
What are the five main categories of inputs to the hypothalamus?
- Nucleus of the solitary tract
- Reticular formation
- Retina
- Amygdala, hippocampus and the olfactory cortex
- Intrinsic hypothalamic receptors
What kind of inputs does the nucleus of the solitary tract send to the hypothalamus?
Visceral sensory information from the glossopharyngeal nerve (blood pressure) and vagus information (gut distension?
Where does the hypothalamus receive: Visceral sensory information from the glossopharyngeal nerve (blood pressure) and vagus information (gut distension) from?
The nucleus of the solitary tract
What kind of inputs does the reticular formation send to the hypothalamus?
Inputs from the spinal cord including information about skin temperature which is relayed to the hypothalamus
What kind of inputs does the Retina send to the Hypothalamus?
Some fibers from the optic nerve go directly to the suprachiasmatic nucleus to regulate circadian rhythm
Where does the hypothalamus receive Inputs from the spinal cord including information about skin temperature which is relayed to the hypothalamus?
The Reticular formation
Where does the hypothalamus receive information about light/dark to regulate circadian rhythms?
The retina
What kinds of inputs do the Amygdala, hippocampus and the olfactory cortex send to the hypothalamus?
Inputs that help to regulate behaviours such as eating and reproduction
Where does the hypothalamus receive inputs to control behaviour like eating and reproduction?
The amygdala, hypothalamus and olfactory cortex
What do the intrinsic receptors of the hypothalamus regulate?
Thermoreceptors, osmoreceptors that measure temperature and ionic balance
How can the hypothalamus be involved in HR regulation?
- The NTS can sample blood oxygen and co2 concentration from the heart and send this information to the hypothalamus
- In response the hypothalamus can send outputs via the DMNV to alter heart rate
Where do autonomic afferents project back to and for what?
The hypothalamus instead of the thalamus for regular senssation
What projects back to the hypothalamus instead of the thalamus?
Autonomic afferents
What happens after autonomic afferent project back to the hypothalamus instead of the thalamus?
The hypothalamus then projects outward and has an effect that is not under conscious control
What are the two main nuclei of the hypothalamic limbic system?
- Lateral Hypothalamic nuclei
- Ventromedial nucleus
What are the lateral hypothalamic nuclei and the ventromedial nuclei apart of?
The Hypothalamic limbic system
What is the Lateral hypothalamic nuclei transversed by?
Longitudinally by many fibres including the medial forebrain bundle
What does the medial forebrain bundle traverse?
The lateral hypothalamic nuclei
What is lateral hypothalamic area important for?
The control of food and fluid intake (desire to eat)
What controls the desire to eat?
The lateral hypothalamic nuclei
What do lesions to the hypothalamic nuclei cause?
Aphagia and adipsia
What is the ventromedial nucleus involved in?
The control of food and fluid intake
What controls the desire to stop eating?
The ventromedial nucleus
What do lesions to the ventromedial nucleus cause?
Abnormally increased food intake
What are the three main hypothalamic efferents?
- Pituitary gland
- Autonomic nervous system
- Limbic system
What is the endocrine section of the hypothalamic efferents?
The pituitary gland
What is the autonomic nervous system portion of hypothalamic efferents?
The vagus nerve
What structures are part of the limbic system hypothalamic efferents?
The amygdala and the hippocampus
How does the hypothalamus use the pituitary as an efferent?
The hypothalamus has control over hormone production (anterior lobe) or hormone release (posterior lobe) of the pituitary gland
What does the hypothalamus use the autonomic nervous system for as an efferent?
To control internal organs
What does the hypothalamus use the limbic system for in terms of efferents?
The hypothalamus initiates appropriate instinctual motor behavior repertoires (such as feeding)
What unites at the hypothalamus?
The autonomic and endocrine systems
What are the superior structures of the brain?
The cerebrum, thalamus and hypothalamus
What are the lower structures of the brain?
Midbrain, pons and cerebellum
What is the middle strucutres of the brain?
The hypothalamus which projects to the pituitary
What are the two parts of the pituitary?
The Adenohypophysis (anterior)
The Neurohypophysis (posterior)
What kind of gland is the pituitary?
An endocrine gland or a neuroendocrine gland
What is the hormone producing part of the pituitary?
The Adenohypophysis
What is the hormone releasing part if the pituitary?
The neurohypophysis
What is the Median eminence?
The projection of the hypothalamus to the posterior pituitary
What is the infundibulum?
The connection of the pituitary to the hypothalamus
What is the pituitary protected by?
Bone and surrounded by the hypophyseal fossa