lecture 18: systemic conditions Flashcards
what is anemia
Reduction of RBC volume (eg. Hematocrit) or
hemoglobin concentration
or low iron
what are some reasons for Reduction of RBC volume (eg. Hematocrit) or
hemoglobin concentration
Impaired RBC formation, excessive loss, or destruction of RBC
what is the function of iron in the form of hemoglobin
- Carries oxygen
- Storage in muscles
- Transport of electrons
- Helps with enzyme reactions
true or false: insuffienct iron amoutns is acceptable
false Insufficient amounts of iron can interfere with vital function and lead to serious illness or even death
what does anemia reduce in terms of physical excerise
- Maximum aerobic capacity
- Decreases physical work capacity at submax levels
- Increases lactic acidosis
- Increases fatigue
- Decreases time to exhaustion
true or false: anemia increases lactic acidosis
true
anemia reduces or increases max aerpbic capaity
reduces
anemia decreases of incnreases physical work capacity and sub max levels
decreases
true or false: you get more easily faituged with anemia
true
what are some SS of anemia
palpitations, fatigue, muscle burning, nausea,
SOB, appetite for substances with little or no
nutritional value, spoon shaped nails, drying scaling
and fissures of lips, inflammation of tongue
why may there be msucle burning in anemia
not able to properly remove CO2 and waste because the lack of iron/hemoglobin therefore theres no 02 coming in
what is a sign of anemia in the hands
spoon shaped nails
what is a sign of anemia in the tongue
inflammationn of the tonngue
what are some predisoping factors for anemia
- Family history
- Poor diet (fad diets, disordered eating) or dietary restrictions (vegetarian)
- Excessive menstrual flow/pregnancy/childbirth
- Chronic bleeding
- Disadvantaged socioeconomic background
- Chronic use of aspirin or NSAIDs
- Cancer
- Volunteer blood donor
- Diminished hepatic, renal or thyroid dysfunction
true or false: diet does not contribute to anemia
false, a poor diet (fad diets, disordered eating) or dietary resitrictions like vegetarian can be a predisposing fator
do meds have an effect on anemia
yes chronic use of aspirin or NSAIDs can be predisposing factors
what is the most common nutritional deficency wordlwide
iron deficency
what population is not as affected by iron defience anemia
not common in men 18+ or post menopausal women
what is the treatment for iron deficeicny anemia
• Increase iron ex: Red meat or dark poultry • Vegetarianàlegumes, grains, nuts/seeds • Iron supplementation
what is the function of vitamin c for anemia
enhances iron absorption
what liquid should you avoid with iron deficency anemia and why
Avoid caffeine products- hinders iron absorption from grains
true or false: there is only 1 type of anemia>?
false there is 3
1) iron defiency anemia
2) exercuse induced hemolytic anemia
3) sickle cell anemia
what is another name for runners anemia
exercise induced hemolytic anemia
what is the main reason behind exrcise induced hemolytic anemia
RBCS are restroyed during exercise
how are rbcs destroyed during exercise
beacuse of repetive trama
explain some reasons because foot strike hemolysis
• Overweight, run on hard surfaces, poor absorption, limited cushioning in shoes
explain some reasons for intravascular hemolysis
• Intravascular hemolysis
• Swimmer, rowers
• Muscle contractions, acidosis or
increased body temperature
can exercise induced hemolytic anemia be improved?
yes AT can help limit the repetive trauma (ex: not hitting the floor so hard when running)
where is the sickle cell gene common?
Sickle cell gene is common in people whose origin is in areas where
malaria is widespread
• Example: Africa, Middle East, Caribbean, South and Central America
is sickle cell anemia more common in white or black people
black peiple
what is sickle cell anemia
Abnormalities in RBC
=Clump together and block vessels, leading to occulusion or infacts in CNS
organs such as heart, lungs, spleen
= Unable to transport oxygen
what is sickle cell anemia attributed to
Inheriting an autosomal recessive gene or to possessing two sickle genes
true or false: sickle cell aneamia is mostly asymptomatic
true
what is the problem with heat/humidity and high altitude in people with sickle cell anemia
may lead to dehydration, increased body temp, hypoxia, acidosis
what are some signs and symptoms associated to oxygen deprivation in sickle cell anemia
Re occurrent bouts of swollen/painful hands/feet, irregular heart beat, muscle
weakness, extreme fatigue, headache, muscle cramping, extreme pain
sickle cell collapse can be mistaken for what
heat collapse or cardiac collapse
what is the onset for sickle cell collapse
often occurs first 30 minutse on the field (core temp not greately elevated)
what is the treatment for sickle cell anemia collapse
Treatment: no cure, hydration is key (dec. caffeine), build up slowly with PA
levels, more rest between reps, acclimatize to altitude and heat, control
asthma etc.
what os the difference between heat cramp and sickle cell in terms of cramping
heat cramping often has a prodrome of muscle twinges (actual spasms) whereas sickle does not
where is the pain greater, in heat cramping or sickle cells
heat cramping pain is more excrutation
what is the difference in the “stopping” during exercise between heat cramp and sickle cell
What stops the athlete is different – heat crampers hobble to a halt with “locked-up” muscles, while sickling players slump to the ground with weak muscles
what is the difference in physical findings b/w heat cramp and sickle cell
heat crampers writhe and yell in pain,
with muscles visibly contracted and rock-hard; whereas,
sicklers lie fairly
still, not yelling in pain, with muscles that look and feel normal
is recovery faster for sicle cell collapse or heat cramping
sickling players caught early and treated
right recover faster than players with major heat cramping (7).
what is the name for bleeding disorder
hemophiliia
hemophilia is caused by a deffiency is what system
clotting system
what are the SS of hemophiliea
large or deep bruises, joint pain and swelling caused by internal bleeding, intramuscular bleeding, blood in urine or stool and prolonged bleeding from procedures
what is lymphangitis
inflammation of the lymphatic channels as a result of infection at a site distal to the vessels
how do pathogenic organisms invate lymphatic vessels
thourgh abraisions/wounds or other infections
what are some SS of lymphangitus
local inflammation, red streaks, headache, loss of appetite,
fevers, chills, malaise, and muscle aches
• Can progress rapidly
what is the treatment for lymphangitis
refer, antibiotics, anti-inflammatory medication, possible drainage
of an absess
red streaks on the skin are associated with what disease
lymphangistus
what is syncompe
sudden LOC “fainting)
hypertension is elevated…
bp
hypertension increases your risk of what
CV disease
what are some risk factors for hypertension
Age, obesity, alcohol abuse, race, sex, smoking, heredity, diabetes
what is the values for pre hypertensive hypertension
120-139
or 80-89
what is stage 1 hyprtension
140-159 or 90-99
hypotension is an elevated or decreased BP
lower bp
what is the problem with hypotension
inadeqate blood circulated to heart and vital organs
what is sudden cardiac death
Unexpected death resulting from sudden cardiac arrest shortly after
exertion (<1 hours) where other definitions include any SCD from
exertional or other events due to acquired coronary artery disease.
what is the leadingn cause of death in young adults
sudden cardiac death
who is at a higher risk for suden cardiac death
males, black athletes and basketball players
are women or men more likely to have an increased death rate for sudden cardica death
men
what is the most common cause of sudden cardiac death in individuals younger than 35 years
hyertrophic cardiomyotpathy
what is hyperrtophic cardiomyotpahy
abnormal thickeneinng of left ventricle wall
true or false: during routine physical examination, hypertrophic cardiomyotpathy
false, it can go undetetcted
what is the normal left venticle size vs hypertrophic cardiomyophaty
normal 1cm
HCM greater than 3 cm
when is Hypertrophic cardiomyotathy suspected in young atheletes
Suspected in young athlete with exertional dyspnea, chest pain,
unexplained syncope, palpitations or prior recognition of heart
murmur
what is the problem with a larger left ventricle
can lead to electrical problems and abnornal rhythems
what is myocarditis
Inflammatory condition of the muscular walls due to bacterial or viral infection
• Abnormally enlarged left ventricle
what is the problem with inflammation of the musclarwalls of the heart
can lead to degenration or death of muscle cells
what can myocarditis cause
electrical isntability and life threathening arryhtmias
what are tthe SS of myocarditus
maybe asymptomatic, fever, body aches, fatigue, cough or vomiting
• Exercise intolerance, SOB, and more serious cardiac symptoms
does marfan symftom lead to SCD
not necessary but it can lead to a weakened aorta q
what is marfan syndrome and what can it affect
Genetic disorder of the
connective tissue that can affect the skeleton, lungs, eyes, heart and blood vessels
• Single mutant gene, usually
inherited
what are some SS of marfan syndrome
overly long extremities
• Joint hypermobile
- Pigeon chest (sunken chest)
- Stretch marks
- Scoliosis
- Increased incidence of hernias
- Positive thumb test and wrist test
what is the positive of the chest for marfan syndrome
pigeon chest (sunken chest)
what is a headache
Irritation of one or more of the pain0sentitive structures or tissues in
the head/neck
• Including cranial arteries and veins, CN’s and spinal nerves, cranial and
cervical muscles, and the meninges.
what are some causes of headaches
- Organic disorders (toxins, systemic diseases)
- Psychoneurological problems (nervous tension, fatigue, worry, excitement)
• Environmental (head trauma, bright lights, noise, altitude change, sunstroke,
motion sickness or irritants like smoke, pollen)
how long do migraine headaches usually alst
4-72 hours
who are more likelt to get migraines and why
women because of change in estrogen levels that are linked to migraines
what are some common ttriggers for migaines
Common triggers- caffeine, missed meals, too much or little sleep, stress, bright
lights, strong odors, change in altitude, red grapes, aspartame
explain migraines without aura
Pulsating quality, aggravated by PA, nausea, photo/phonophobia, desire to lay down
in dark room
explain migraines with aura
Develops over 5 min and last 60 min
• Unilateral visual, sensory, and other sensory or CNS symptoms such as reversible
changes in speech, motor or visual chances
what is the most common type of headache
tension type headaches
where are tension type headaches most common (what part of brain)
Typically in frontal or occipital region bilaterally spreading over the
entire head
• Pressing or tightening quality