Lecture 18: Male Reproductive System Flashcards

1
Q

4 functions of male reproductive organs

A
  1. Production of male sex cells
  2. Production of the male sex hormone testosterone
  3. Introduction of male gametes into the female reproductive organs
  4. Production of other hormones such as PMDH/AMH in male embryo and inhibin in adult
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2
Q

Where is the site of spermatogenesis

A

Testis

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3
Q

Where is the site of the production of sex hormones

A

Testis

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4
Q

Parenchyma of testes is composed of

A

Seminiferous tubules with sertoli cells

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5
Q

Interstitium of testes contains

A

Interstitial cells of leydig

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6
Q

Two testicular tunics

A
  1. Tunicae vaginalis

2. Tunica albuinea

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7
Q

Tunica vaginalis is composed of

A

Mesothelium and a connective layer

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8
Q

Two components of the tunica vaginalis

A
  1. Parietal, which blends and is attached to the CT of the scrotum
  2. Visceral, surrounds the testis and the epididymis
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9
Q

Tunica albuginea

A

A capsule of dense connective tissue composed to collagen fibers, a few elastic fibers and myofibroblasts

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10
Q

Tunica albuginea is continuous with

A

Connective tissue trabeculae named septule testis

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11
Q

What separates the seminiferous tubules

A

Septule testis

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12
Q

Seminiferous tubules are lined by

A

spermatogenic epithelium

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13
Q

What are located between seminiferous tubules

A

Leydig

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14
Q

Spermatogenic epithelium is surrounded by

A

Lamina propria of collagen and elastic fibers

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15
Q

What are the most immature spermatogenic cells

A

spermatogonia

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16
Q

Spermatogonia lies next to

A

the basement membrane

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17
Q

Spermatic pathway

A
  1. Seminiferous tubules
  2. Tubuli recti
  3. Rete testis
  4. Efferent ductules
  5. Epididymal duct
  6. Ductus Vas deferens
  7. Pelvic urethra
  8. Penile urethra
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18
Q

Seminoma

A

Composed of intratubular neoplastic cells with characteristics of seminiferous cells, which are compressing adjacent tubules

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19
Q

Sertoli cells are characterized by

A

Presence of tight junctions that divide the seminiferous epithelium into a basal and adluminal compartment

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20
Q

Six functions of sertoli cells

A
  1. Support, protect, nourish spermatogenic cells
  2. Secrete supporting testicular fluid
  3. Protect (via tight junctions) spermatids from the immune system
  4. Have receptors for SH, which results in a release of androgen binding protein, which binds to androgens and influences germ cell differentiation
  5. Synthesizes anti-Mulleriuan hormone in the embryo and prevents the formation of the mullerian duct and oviduct
  6. Releases hormone inhibin which suppresses secretion of FSH
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21
Q

Nucleus of Leydig cells

A

small, round, euchromatic, and eccentric

22
Q

Cytoplasm of Leydig cells

A

Acidophilic and foamy due to lipid presence

23
Q

What do Leydig cells secrete

A

Testosterone

24
Q

What are Leydg cells controlled by

A

Interstitial cells stimulating hormone (ICSH)

25
Testosterone is produced by
Leydig cells
26
Three androgenic responsibilities of testosterone
1. Responsible for secondary male sex characteristics 2. Sex drive 3. Stimulates development and secretory activity of male sex accessory glands
27
Anabolic effect of testosterone
Stimulates growth of skeletal muscles and bones
28
4 things the spermatic cord is composed of
1. Testicular artery 2. Testicular vein 3. Lymphatics 4. Ductus deferens
29
Seminiferous tubules terminate...
As straight testicular tubules that empty into the anastomising channels of the rete testis
30
What lines the rete testis
Simple squamous to cuboidal
31
Rete testis empties into
efferent ductules which lead to the epipidymal duct
32
Epididymal ductis lined by
Psuedostratified columnar epithelium with stereocilia
33
Three main functions of epididymal duct
1. Fluid resorption (90%) 2. Secretion of glycerophosphocholine 3. Site of sperm storage (in the tail)
34
What is the ductus deferens lined by
Pseudostratified columnar epithelium with stereocilia
35
Ductus deferens is characterized by
Prominent muscularis = peristaltic contractions that propel spermatozoa
36
Terminal portion of the ductus deferens
ejaculatory duct
37
Ampulla
A male accessory gland located near the junction of the urethra and the ductus deferens in ruminants
38
4 Accessory sex glands
1. Bulbourethral glands 2. Prostate gland 3. Ampullary gland 4. Vesicular gland (seminal vesicles)
39
Accessory glands are lined by
simple or psuedostratified epithelium
40
What accessory glands are tubuloalveolar
All of them
41
Seminal vesicles are lined by
psuedostratified epithelium with tall columnar cells and basal cells
42
Are vesicular glands present in carnivores?
Nope
43
Purpose of seminal vesicles
Produce fructose which is the source of energy for sperm cells
44
Prostate
Multilobulated gland that surrounds the prostatic urethra
45
Prostate is surrounded by
a fibroelastic capsule
46
Prostate is lined by
simple cuboidal to columnar, sometimes psuedostratified epithelium
47
What is often seen in the lumen of the prostate gland
corpora amylacea
48
What kind of muscle surrounds the prostate gland
smooth
49
Bulbourethral glands empty into the
pelvic urethra
50
Bulbourethral glands are lined by
tall simple cuboidal/columnar epithelium
51
What acts as a lubricant in the urethra?
Mucous secretion
52
Three portions of the male urethra
1. Prostatic 2. Pelvic 3. Penile