Lecture 12

Question 1

3activation of helper T requirement

Answer 1

MHC II(dendritic)& peptide(T)
B7(dendritic)& CD28(T)
cytokine release by APC

Question 2

3 step B cell as APC

Answer 2

take in antigen
break apart
put onto surface via MPC II

Question 3

5 class of AB

Answer 3

IgG: most abundant, cross placenta
IgA: MALT& breast milk
IgM: first formed, activate complement cascade
IgD
IgE: allergy

Question 4

4 kinds of immunity

Answer 4

active
natural: expose to antigen, produce memory cell
artificial: vaccine, produce memory cell

passive
natural: IgG across placenta, IgA from breast milk(intestinal mucosa肠粘膜 permeable)
artificial: receive convalescent serum w/ AB, fight Ebola& COVID

Question 5

function of AB

Answer 5

neutralize antigen

agglutination of antigen

precipitation of antigen

activate complement
C1 complement, membrane attack complex

opsonization

AB dependent cellular cytotoxicity