Lecture 06 Flashcards
circulatory system 血管
artery, arteriole, capillary bed, ventriole, vein
blood hydrostatic pressure& COP的5个对应数
heart contract: 120mmHg
heart relax: 80mmHg
arteriole side of capillary: 35mmHg
ventriole side of capillary: 15mmHg
COP: 25mmHg
% reabsorbed back to capillaries, % drained from tissue by lymphatic vessel
90% reabsorbed back to capillaries, 10% drained from tissue by lymphatic vessel
lymphatic vessel 4 features
blind ended, dead end, fluid only move one way
single cell layered wall
more permeable than capillary wall
can pick up protein
2 factors of osmotic pressure
directly related to concentration in plasma
inversely related to MW
word for “accumulation of excess fluid in the interstitial space”
edema
4 conditions lead to edema
increased hydrostatic pressure
decreased COP
increased capillary permeabiliy
obstruction of lymphatic drainage
3 causes of decreased COP
liver disease, not able to produce protein
renal disease, lsoe protein into urine
severe protein malnutrtion, do not have enough protein in the diet
word for “severe protein malnutrtion”
kwashiorkor/ deposed child syndrome
2 causes of obstruction of lymphatic drainage
people undergo breast cancer treatment, remove breast, remove lymphatic region in arm region, decrease venous return
lesion at extremities四肢, Filaria nematode丝虫线虫 come into circulatory system, adult worm blockage of lymphatic return, Elephantiasis
3 roles of plasma protein
determine distribution of fluid btw ISF& plasma by Starling forces
viscosity, pressure
buffer power of plasma
specific 3 plasma protein function
fibrinogen& some globulin: clotting
gamma globulin/ immunoglobulin: resistance to infection
albumin and some globulinL carrier for lipid, mineral, hormone
eg for “albumin and some globulinL carrier for lipid, mineral, hormone”
Fe free form toxic, bound to protein not harm tissue
