Lecture 04 Flashcards
4 step of secondary active transport
Na high outside
Na bind to Na binding site & solute bind to solute binding site
change conformation, Na & solute release into cell
transporter revert to original configuration
word for “solute& Na same direction”
cotransport/ symport
eg for cotransport/ symport
Na/HCO3-, Na/AA, Na/glucose
word for “solute& Na different direction”
countertransport/ antiport
eg for countertransport/ antiport
Na/H, Na/Ca
significance of Na/Ca exchanger
need to keep Ca low in heart/ muscle cell, otherwise cell stay contracted
3 types of endocytosis
pinocytosis, phagocytosis, receptor mediated endocytosis
4 steps of phagocytosis
cell bind small sized dust particle/ cell debris/ microorganism
trigger phagocytosis
pseudopodia fold around the particle and fully engulf it
form vesicle called phagosome
2 types of receptor mediated endocytosis
clathrin dependent receptor mediated endocytosis
potocytosis
5 step for LDL clathrin dependent receptor mediated endocytosis
LDL bind to receptor on CM
trigger formation of vesicle, trigger movement of clathrin
vesicle pinch off, form clathrin coated vesicle
vesicle shed clathrin in the cell, fuse with membrane, deposit its good within endosome
deposit go directly to lysosome/ recycle back to CM/ repackage the vesicle and transport for export on another CM
special vesicle in potocytosis& 3 function
caveolae
fuse with CM& internalize into cell& release content directly into cytoplasm
2 types of exocytosis
constituitive exocytosis
regulated exocytosis
1 eg of regulated exocytosis& process
synapse
vesicle store Ach, signal come along, Ca enter through Ca channel, fusion of vesicle w/CM& release of Ca into synapse
word for “the net diffusion of H2O across a semipermeable membrane”
osmosis
word for “the pressure required to prevent movement of H2O across semipermeable membrane”
osmotic pressure
