Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology II > LEC 14 - GI V > Flashcards

LEC 14 - GI V Flashcards

1
Q

What does the parvovirus type 2 infect in regards to cell type?

A

Dividing cells in the crypts of the intestines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of tropism does parvovirus type 2 have?

A

Radiomimetric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where does initial replication occur in parvovirus?

A

Lymphoid tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the early lesions seen with Parvoviral enteritis?

A

Lymphoid depletion

Thymic involution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the late stage lesions seen with Parvoviral enteritis?

A

Red

Fibrinous exudate in lumen

Flaccid segments of SI

Serositis

Depletion of bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What late lesion is only seen in dogs with parvoviral enteritis?

A

Coagulative lymphadenitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens to cats when they are infected with parvovirus type 2 in utero?

A

Cerebellar hypoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What causes cerebellar hypoplasia in cats that get an in utero parvo virus infection?

A

Alteration of differentiation of layers in cerebellum at organogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is seen upon histological examination of parvoviral enteritis?

A

Villus atrophy due to crypt destruction

Intranuclear basophilic inculsion bodies

Enterocytes + Lymphocytes infected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are other names for parvoviral enteritis in cats + minks + raccoons?

A

Panleukopenia

Cat distemper

Feline enteritis

Mink enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What dog breeds are at an increase risk of parvo virus infection?

A

Rottweilers

Dobermans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Canine parvovirus syndrome: < 2 weeks

A

Generalized disease

Necrosis of rapidly dividing tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Canine parvovirus syndrome: 3 to 8 weeks

A

Myocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Canine parvovirus syndrome: > 8 weeks

A

Hemorrhagic enteritis

Panleukopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the gross presentation of parvoenteritis?

A

Segments of SI diffusely reddened

Serosal surface is roughened + faintly granular + petechiated

Mucosa necrotic

Sloughing mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the cause of minute virus of canids?

A

Canine Parvovirus Type 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is present in minute virus of canids?

A

Myocarditis + Respiratory disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

When does minute virus of canids cause fetal death?

A

If infection occurs at 25 to 35 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What causes feline infectious peritonitis?

A

Feline enteric mutated coronavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the two forms of FIP?

A

Wet

Dry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Describe: Dry form of FIP

A

No effusion occurs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Describe: Wet Form of FIP

A

Fibrinous polyserositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What cell type does feline enteric mutated coronavirus infect?

A

Macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Where does inital replication of feline enteric mutated coronavirus occur?

A

Lymphoid tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What is the pathogensis of FIP?

A

Intital replication in lyphoid tissue

Macrophages infection

Carry virus systemic

Endothelial cells activated due to upregulation of MHC II

Non-neutralizing Ab’s

Immunocomplexes form

Vasculitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What is the gross presentation of the wet form of fibrinous polyserositis?

A

Fibrin strands between viscera

Mats of fibrin on organ surfaces

White linear serpentine tracts in mesentery

Small nodules of intestinal serosa + surface of kidney

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What causes the white linear serpentine tracts in FIP?

A

Type II hypersensitivity

due to immune complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What is the bacterial cause of histiocytic ulcerative colitis?

A

Suggest that it might be E. Coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What population of dogs tend to get histiocytic ulcerative colitis?

A

Boxer dogs

Younger then 2 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What gross lesions are seen with histiolytic ulcerative colitis?

A

Raised ulcerative nodules in colon

Lymphadenopathy

(Can be regional or generalized)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What is the histopathology of histiocytic ulcerative colitis?

A

Ulceration

Marked inflammation reaction (Composed of macrophages + intracytoplasmic PAS postive material)

In lamina propria of mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What is the fungal cause of canine histoplasmosis?

A

Histoplasma capsulatum

33
Q

Where is canine histoplasmosis most commmonly seen?

A

Ohio

Mississippi river valleys

34
Q

How are dogs infected with canine histoplasmosis?

A

Yeast is inhaled or ingested

Invades tissues

Replicates in macrophages

Causes necrosis + granulomatous inflammation

35
Q

What does the GI form of canine histoplasmosis look like grossly?

A

Mucosa is corrugated + thickened with ulceration

Granulomas in liver

Hepatomegaly

Lymphadenomegaly

36
Q

Where can you see the microorgranism when a canine histoplasmosis infection is occurring?

A

Inside macrophages of lamina proria or ileum and colon

37
Q

What organism causes salmon poisoning?

A

Neorickettsia hemlinthoeca

38
Q

What is the basic life cyle of a neorickettsia hemlinthoeca?

A

Lives in a trematode

Affects salmon

Salmon ingested by a dog

39
Q

What does neorickettsia hemlintoeca cause in a dog?

A

Necrosis of the GALT near the ileocecal valve

40
Q

What gross lesions are seen with salmon poisoning?

A

Hemorrhagic + Granulomatous enterocolitis

41
Q

What provides a diagnosis of salmon poisoning?

A

Macrophages containing Giemsa OR Gram-stained elementary bodies

42
Q

How long does it take a dog to die from salmon poisoning?

A

10 days

43
Q

What causes canine multifocal eosinophilic enteritis?

A

Larvae of Toxocara canis

44
Q

At what age is canine multifocal eosinophilic enteritis most common?

A

Younger than 4 years

45
Q

What happens when larvae of the Toxocara are in the mucosa in the GI tract?

A

Granulomatous nodules

46
Q

What is the pathogenesis of Canine multifocal eosinophilic enteritis?

A

Larvae ingested

Invade mucosa of stomach + SI

Enter lymph vessels OR portal vein

Travel to liver + lung

L3 coughed up + swallowed

Mature/adult develops GI tracts

47
Q

What is the characteristics of inflammatory bowel disease?

A

Lymphoplasmacytic enteritis

48
Q

What breed are predisposed to inflammatory bowel disease?

A

Basejii

German Shepherd

49
Q

What is the cause inflammatory bowel disease?

A

Unknown

50
Q

What can inflammatory bowl disease in cats lead to?

A

Alimentary lymphoma

51
Q

What dog breeds are predisposed to difffuse eosinophilic gastroenteritis?

A

German shepherd

52
Q

Describe: Diffuse eosinophilic gastroenteritis

A

Increase in tissue + circulating eosinophilia

Suggests an hypersensitivity reaction

53
Q

What gross lesions are present in diffuse eosinophilic gastroenteritis?

A

None

54
Q

What is canine senile gastrointestinal amyloidosis characterized by?

A

Amyloid deposition in/around vessels of submucosa + muscularis layers

55
Q

What disease processes are seen with canine senile GI amyloidosis?

A

No dysfunction seen

56
Q

What does feline ulcerative colitis look like?

A

Histiocytic uclerative colitis in dogs

57
Q

What does lymphagiectasia cause?

A

Protein-losing enteropathy in dogs

58
Q

What is the cause of congenital lymphangiectasia?

A

Developmental disorders of lymphatics vessels

59
Q

What is the cause of acquired lymphangiectasia?

A

Lymph vessels obstruction

60
Q

What gross lesions are seen with lymphangiectasia?

A

Thickened mucosa with dialated lymphatics + lacteals in intestine

61
Q

What can idiopathic intestinal lymphangiectasia lead to? Why?

A

Ascites due to protein-losing enteropathy

62
Q

What is ileus?

A

Paralytic ileus is non-mechanical hypotitity resulting in functional obstruction

63
Q

What can cause Ileus?

A

Paralysis of the wall

Peritonitis

Abnormal stimulation of splanchinic n.

Toxemia

Vitamin B-Complex deficiency

Uremia

Tetanus

64
Q

Term: Trapped section in intussuception

A

Intussusceptum

65
Q

Term: Enveloping portion in intussusception

A

Intussuscipiens

66
Q

What breed of horse most commonly gets enteroliths?

A

Arabian breeds

Older than 4 years ofl

67
Q

What are enteroliths most commonly made of?

A

Ammonium-magnesium phosphate

(Struvite)

Around a central nidus

68
Q

Where do enteroliths normally lodge?

A

Pelvic flexure

– or –

Transverse colon

69
Q

What commonly result in strictures?

A

Narrowing of the lumen of a canal

Normally due to healing of a scar

70
Q

What is a common cause of a stricture in pigs?

A

Sequela of Salmonellosis

Thrombosis of cranial hemorrhoidal artery

71
Q

What is atresia?

A

Occulsion of intestinal lumen as the result of anomalous development

72
Q

How does atresia occur?

A

Result from lesions in fetal blood vessels

Most of the time caused by malpositioning + secondary vascular accidents/ischemia

73
Q

What are the forms of Megacolon?

A

Acquired

– and –

Congenital

74
Q

What animals does the congenital form of megacolon occur in

A

Pigs

Dogs

Cats

Overo foals

75
Q

What is the cause of congenital megacolon?

A

Developmental lack of myenteric plexus secondary to failure of migration of neuroblasts from neural crest

76
Q

What histological lesions are seen with equine overo?

A

Intestinal aganglionosis

77
Q

What occurs with equine overo megacolon?

A

Colic develops

Die within 72 hours of birth

78
Q

What causes acquired megacolon?

A

Secondary to damage to the colonic inervation

Atresia ani

Pathology II (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions