Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pathology II > LEC 14 - GI V > Flashcards

LEC 14 - GI V Flashcards

1
Q

What does the parvovirus type 2 infect in regards to cell type?

A

Dividing cells in the crypts of the intestines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What type of tropism does parvovirus type 2 have?

A

Radiomimetric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where does initial replication occur in parvovirus?

A

Lymphoid tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the early lesions seen with Parvoviral enteritis?

A

Lymphoid depletion

Thymic involution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the late stage lesions seen with Parvoviral enteritis?

A

Red

Fibrinous exudate in lumen

Flaccid segments of SI

Serositis

Depletion of bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What late lesion is only seen in dogs with parvoviral enteritis?

A

Coagulative lymphadenitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens to cats when they are infected with parvovirus type 2 in utero?

A

Cerebellar hypoplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What causes cerebellar hypoplasia in cats that get an in utero parvo virus infection?

A

Alteration of differentiation of layers in cerebellum at organogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is seen upon histological examination of parvoviral enteritis?

A

Villus atrophy due to crypt destruction

Intranuclear basophilic inculsion bodies

Enterocytes + Lymphocytes infected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are other names for parvoviral enteritis in cats + minks + raccoons?

A

Panleukopenia

Cat distemper

Feline enteritis

Mink enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What dog breeds are at an increase risk of parvo virus infection?

A

Rottweilers

Dobermans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Canine parvovirus syndrome: < 2 weeks

A

Generalized disease

Necrosis of rapidly dividing tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Canine parvovirus syndrome: 3 to 8 weeks

A

Myocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Canine parvovirus syndrome: > 8 weeks

A

Hemorrhagic enteritis

Panleukopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the gross presentation of parvoenteritis?

A

Segments of SI diffusely reddened

Serosal surface is roughened + faintly granular + petechiated

Mucosa necrotic

Sloughing mucosa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the cause of minute virus of canids?

A

Canine Parvovirus Type 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is present in minute virus of canids?

A

Myocarditis + Respiratory disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

When does minute virus of canids cause fetal death?

A

If infection occurs at 25 to 35 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What causes feline infectious peritonitis?

A

Feline enteric mutated coronavirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the two forms of FIP?

A

Wet

Dry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Describe: Dry form of FIP

A

No effusion occurs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Describe: Wet Form of FIP

A

Fibrinous polyserositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What cell type does feline enteric mutated coronavirus infect?

A

Macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Where does inital replication of feline enteric mutated coronavirus occur?

A

Lymphoid tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is the pathogensis of FIP?
Intital replication in lyphoid tissue Macrophages infection Carry virus systemic Endothelial cells activated due to upregulation of MHC II Non-neutralizing Ab's Immunocomplexes form Vasculitis
26
What is the gross presentation of the wet form of fibrinous polyserositis?
Fibrin strands between viscera Mats of fibrin on organ surfaces White linear serpentine tracts in mesentery Small nodules of intestinal serosa + surface of kidney
27
What causes the white linear serpentine tracts in FIP?
Type II hypersensitivity due to immune complexes
28
What is the bacterial cause of histiocytic ulcerative colitis?
Suggest that it might be E. Coli
29
What population of dogs tend to get histiocytic ulcerative colitis?
Boxer dogs Younger then 2 years
30
What gross lesions are seen with histiolytic ulcerative colitis?
Raised ulcerative nodules in colon Lymphadenopathy (Can be regional or generalized)
31
What is the histopathology of histiocytic ulcerative colitis?
Ulceration Marked inflammation reaction (Composed of macrophages + intracytoplasmic PAS postive material) In lamina propria of mucosa
32
What is the fungal cause of canine histoplasmosis?
Histoplasma capsulatum
33
Where is canine histoplasmosis most commmonly seen?
Ohio Mississippi river valleys
34
How are dogs infected with canine histoplasmosis?
Yeast is inhaled or ingested Invades tissues Replicates in macrophages Causes necrosis + granulomatous inflammation
35
What does the GI form of canine histoplasmosis look like grossly?
Mucosa is corrugated + thickened with ulceration Granulomas in liver Hepatomegaly Lymphadenomegaly
36
Where can you see the microorgranism when a canine histoplasmosis infection is occurring?
Inside macrophages of lamina proria or ileum and colon
37
What organism causes salmon poisoning?
Neorickettsia hemlinthoeca
38
What is the basic life cyle of a neorickettsia hemlinthoeca?
Lives in a trematode Affects salmon Salmon ingested by a dog
39
What does neorickettsia hemlintoeca cause in a dog?
Necrosis of the GALT near the ileocecal valve
40
What gross lesions are seen with salmon poisoning?
Hemorrhagic + Granulomatous enterocolitis
41
What provides a diagnosis of salmon poisoning?
Macrophages containing Giemsa OR Gram-stained elementary bodies
42
How long does it take a dog to die from salmon poisoning?
10 days
43
What causes canine multifocal eosinophilic enteritis?
Larvae of Toxocara canis
44
At what age is canine multifocal eosinophilic enteritis most common?
Younger than 4 years
45
What happens when larvae of the Toxocara are in the mucosa in the GI tract?
Granulomatous nodules
46
What is the pathogenesis of Canine multifocal eosinophilic enteritis?
Larvae ingested Invade mucosa of stomach + SI Enter lymph vessels OR portal vein Travel to liver + lung L3 coughed up + swallowed Mature/adult develops GI tracts
47
What is the characteristics of inflammatory bowel disease?
Lymphoplasmacytic enteritis
48
What breed are predisposed to inflammatory bowel disease?
Basejii German Shepherd
49
What is the cause inflammatory bowel disease?
Unknown
50
What can inflammatory bowl disease in cats lead to?
Alimentary lymphoma
51
What dog breeds are predisposed to difffuse eosinophilic gastroenteritis?
German shepherd
52
Describe: Diffuse eosinophilic gastroenteritis
Increase in tissue + circulating eosinophilia Suggests an hypersensitivity reaction
53
What gross lesions are present in diffuse eosinophilic gastroenteritis?
None
54
What is canine senile gastrointestinal amyloidosis characterized by?
Amyloid deposition in/around vessels of submucosa + muscularis layers
55
What disease processes are seen with canine senile GI amyloidosis?
No dysfunction seen
56
What does feline ulcerative colitis look like?
Histiocytic uclerative colitis in dogs
57
What does lymphagiectasia cause?
Protein-losing enteropathy in dogs
58
What is the cause of congenital lymphangiectasia?
Developmental disorders of lymphatics vessels
59
What is the cause of acquired lymphangiectasia?
Lymph vessels obstruction
60
What gross lesions are seen with lymphangiectasia?
Thickened mucosa with dialated lymphatics + lacteals in intestine
61
What can idiopathic intestinal lymphangiectasia lead to? Why?
Ascites due to protein-losing enteropathy
62
What is ileus?
Paralytic ileus is non-mechanical hypotitity resulting in functional obstruction
63
What can cause Ileus?
Paralysis of the wall Peritonitis Abnormal stimulation of splanchinic n. Toxemia Vitamin B-Complex deficiency Uremia Tetanus
64
Term: Trapped section in intussuception
Intussusceptum
65
Term: Enveloping portion in intussusception
Intussuscipiens
66
What breed of horse most commonly gets enteroliths?
Arabian breeds Older than 4 years ofl
67
What are enteroliths most commonly made of?
Ammonium-magnesium phosphate (Struvite) Around a central nidus
68
Where do enteroliths normally lodge?
Pelvic flexure -- or -- Transverse colon
69
What commonly result in strictures?
Narrowing of the lumen of a canal Normally due to healing of a scar
70
What is a common cause of a stricture in pigs?
Sequela of Salmonellosis Thrombosis of cranial hemorrhoidal artery
71
What is atresia?
Occulsion of intestinal lumen as the result of anomalous development
72
How does atresia occur?
Result from lesions in fetal blood vessels Most of the time caused by malpositioning + secondary vascular accidents/ischemia
73
What are the forms of Megacolon?
Acquired -- and -- Congenital
74
What animals does the congenital form of megacolon occur in
Pigs Dogs Cats Overo foals
75
What is the cause of congenital megacolon?
Developmental lack of myenteric plexus secondary to failure of migration of neuroblasts from neural crest
76
What histological lesions are seen with equine overo?
Intestinal aganglionosis
77
What occurs with equine overo megacolon?
Colic develops Die within 72 hours of birth
78
What causes acquired megacolon?
Secondary to damage to the colonic inervation Atresia ani

Pathology II (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions