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OS 217 Infectious Diseases > Lec 03 Principles of Vaccinology and Guidelines > Flashcards

Lec 03 Principles of Vaccinology and Guidelines Flashcards

1
Q

T/F Vaccines save lives

A

F. No! Vaccination does!

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2
Q

T/F Vaccines must retain pathogenicity but not antigenicity.

A

F. Must maintain antigenicity and not pathogenicity

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3
Q

Non-specific and the body’s first line of defense

A

Innate Immunity

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4
Q

3 major characteristics of Adaptive Immunity

A

Memory, Specificity and Diversity

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5
Q

Active/Passive immunity?
Protection transferred from another person or animals
as antibody

A

Passive

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6
Q

Active/Passive immunity?

Usually permanent

A

Active

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7
Q

– substances added to inactivated vaccines

to increase host response and afford longer protection

A

Adjuvants

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8
Q

Live Attenuated/Inactivated?

MMR

A

Live attenuated

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9
Q

Live Attenuated/Inactivated?

BCG

A

Live attenuated (bacterial)

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10
Q

Protective immunity from inactivated vaccines develops after how many doses?

A

2-3

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11
Q

T/F: NO VACCINE IS COMPLETELY SAFE NOR COMPLETELY EFFECTIVE!

A

True

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12
Q

T/F: Simultaneous administration (administration on
the same day) of the most widely used live and inactivated vaccines doesn’t result in decreased antibody responses or increased rates of ADRs

A

T

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13
Q

There are NO contraindications to simultaneous administration of any vaccine except for cholera and?

A

Yellow fever

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14
Q

T/F: Increasing the interval between doses of a multidose
vaccine does diminishes the effectiveness of the
vaccine.

A

F

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15
Q

T/F: Decreasing the interval between doses of a multidose vaccine may interfere with antibody response and protection.

A

T

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16
Q

T/F: It is not necessary to restart the series of any vaccine
due to extended intervals between doses

A

T

17
Q

Why are the buttocks not routinely used as a site for vaccination?

A

Possible injury to the sciatic nerve

18
Q

Injection sites in the same limb should be separated by at least how many inches so local reactions will not overlap?

A

1 to 2

19
Q

T/F If expiry date is Dec 2013, the vaccine is still viable until Dec 01, 2013.

A

F. Vaccine is viable until Dec 31, 2013

20
Q

ALL vaccines are recommended to be transported and

stored at temperatures of:

A

2 to 8 degrees C

21
Q

Identify severity of anaphylaxis:

Bronchospasm, stridor, collapse, hypotension, dysrhythmias

A

SEVERE

22
Q

Identify severity of anaphylaxis:

Dizziness, perineal burning, warmth, pruritus

A

MILD

23
Q

T/F: Tetanus vaccination of unprotected pregnant

women in developing countries is strongly recommended

A

T

24
Q

Critical vaccination coverage for herd immunity (%) for Measles

A

92-95%

25
Q

T/F: Inactivated vaccines are contraindicated in pregnant patients

A

F

OS 217 Infectious Diseases (22 decks)

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