Learning, memory and higher cognition Flashcards
retrograde amnesia
loss of old memories
anterograde amnesia
inability to form new memories
damage to hippocampus causes
anterograde amnesia, old memories still remain
declarative memories
memories that we are aware we formed, associated with hippocampus
nondeclarative memories
memories shown through performance rather than conscious recollection, associated with amygdala, cerebellum, and basal ganglia
encoding
information goes to short term memory
consolidation
transfer from short to long term memory
retrieval
use of stored information
Anisomycin
antibiotic that inhibits protein synthesis necessary for synaptic changes
Every time a memory is reactivated it undergoes
reconsolidation
Habituation
decreased response to repeated presentation of a stimulus
Sensitization
prior strong stimulation increases response to most stimuli
Nonassociative learning
a single stimulus presented once or repeated
Example of habituation
gill withdrawal response in sea slugs
neurons that fire together
wire together
The number of synapses between the sensory cell and the motor neuron _____ during habituation
decreases
Sensitization typically occurs in the presence of
sudden, novel stimulus
ex. shock presented to the sea slug at the same time as a water jet, enhancing the gill withdrawal response
Sensitization occurs via
a serotonergic interneuron
Long term potentiation
the change in amplitude of an excitatory postsynaptic potential in response to stimulation at a synapse
Long term potentiation is dependent on _____ receptors that work with _____ receptors in CA1
NMDA, AMPA
Normally NMDA and AMPA respond to
glutamate
In the hippocampus, NMDA receptors are blocked by
magnesium ions