β-lactam antibiotics Flashcards
What is the Natural penicillins ?
1- Benzyl penicillin (Penicillin-G)
2- Procaine penicillin
3- Benzathine penicillin (long acting)
4- Phenoxymethyl penicillin (Penicillin-V)
penicillin remains the drug of choice for the treatment of ?
1- gas gangrene
2- syphilis
What is the Acid sensitive ( labile ) (not given orally) ?
1- Benzyl penicillin
2- Procaine penicillin
3- Benzathine penicillin
What is the Acid-resistant (given orally) ?
Phenoxymethyl penicillin
What is the drug of choice for neurosyphilis ?
Penicillin G
What is the uses of natural penicillin ?
1- Treatment of syphilis and Benzathine penicillin
2- Penicillin G is drug of choice for neurosyphilis
3- Most staphylococci and gonococci are now resistant
What is the Penicillinase-resistance penicillins ?
1- Methicillin 2- nafcillin 3- Cloxacillin 4- dicolxacillin 5- flucoxacillin
What is the Acid labile ( sensitive ) in Penicillinase-resistance penicillins ?
1- Methicillin
2- nafcillin
What is the Acid-resistant of Penicillinase-resistance penicillins ?
1- Cloxacillin
2- dicolxacillin
3- flucoxacillin
What is the treatment of MRSA ?
vancomycin or teicoplanin.
What is the treatment of (VRSA) ?
linezolid or streptogramins
Ampicillin is drug of choice for ?
listeria meningitis and urinary tract infection caused by E. faecalis
Ampicillin should be given on ?
empty stomach
Nafcillin is excreted mainly in ?
bile
Methicillin is the most common antibiotic implicated in
causing ?
interstitial nephritis.