Antifungal Flashcards
1
Q
Adverse effects of Amphotericin B :
A
1- renal Toxicity 2- Hypokalemia 3- Hypomagnesaemia 4- Anemia, thrombocytopenia 5- Impaired hepatic function
2
Q
Bind to fungal cell membrane ergosterol ?
A
Amphotricine B and Nystatin
3
Q
Inhibit orgosterol synthesis ?
A
Azoles
4
Q
inhibit of nucleic acid synthesis ?
A
5 - flucytosine
5
Q
Disruption of mitotic spindle and inhibition of fungal mitosis ?
A
Griseofuvin
6
Q
Amphotericin B :
A
Oral administration in GIT fungal infection
7
Q
Amphotericin B increases the ?
A
penetration of 5-FC
