Introduction to antimicrobial therapy

Question 1

Example of Bactricidal ?

Answer 1

penicillins

Question 2

Example of Bacteristatic ?

Answer 2

tetracyclin

Question 3

In the Empirical therapy the antibiotic should ?

Answer 3

cover all the possible pathogens

Question 4

The organism’s susceptibility to the drug ?

Answer 4

1- Minimum inhibitory concentration (MIC)

2- Minimal bactericidal concentration (MBC)

Question 5

Example of Cell wall synthesis inhibitors ?

Answer 5

1- penicillins
2- cephalosporins
3- bacitracin

Question 6

Example of Changes the permeability of cell membrane ?

Answer 6

polymyxin B

Question 7

Example of Interfere with metabolic processes within the microorganism ?

Answer 7

1- sulfonamides
2- trimethoprim
3- isoniazid (INH)

Question 8

Exapmle of Bactricidal ?

Answer 8

1- penicillins

2- aminoglycosides

Question 9

Example of Bacteristatic ?

Answer 9

1- tetracyclin
2- Macrolides
3- tetracyclines
4- chloramphenicol

Question 10

30 s ?

Answer 10

1- aminoglycosides

2- tetracyclines

Question 11

50 s ?

Answer 11

1- Macrolides

2- chloramphenicol

Question 12

Example of Interfere with synthesis of nucleic acid ?

Answer 12

1- fluoroquinolones

2- rifampicin

Question 13

Example of Enhancement of antibacterial activity in the treatment of specific infections ?

Answer 13

Combination of penicillin with gentamicin to treat Sub acute bacterial endocarditis

Question 14

1+1 >2 ?

Answer 14

Synergism

Question 15

0 +1 >1 ?

Answer 15

Potentiation

Question 16

1+1<2 ?

Answer 16

Antagonism

Question 17

What is the mechanisms for drug resistances ?

Answer 17

1- Genetic alterations leading to drug resistance

2- Altered expression of proteins in drug-resistant organisms