Alpha Blocker

Question 1

Example of non-selective alpha- adrenoreceptor blockade ( a1+a2 ) ?

Answer 1

1- phenoxybenzamine

2- phentolamine

Question 2

Example of non-selective alpha- adrenoreceptor blockade ( a1+a2 ) ? ( Reversible antagonists ) ?

Answer 2

Phentolamine

Question 3

Example of non-selective alpha- adrenoreceptor blockade ( a1+a2 ) ? ( irreversible antagonists ) ?

Answer 3

Phenoxybenzamine

Question 4

Give Examples of Reversible antagonists in alpha blocker ?

Answer 4

1- phentolamine
2- Prazosin
3- Terazosin

Question 5

Give Example of irreversible antagonists in alpha blocker ?

Answer 5

Phenoxybenzamine

Question 6

What is the uses of Phenoxybenzamine (block both a1 & a2 ) ?

Answer 6

1- pheochromocytoma

2- Raynaud disease and frostbite

Question 7

What is the uses of Phentolamine block of both

a1 and a2 ?

Answer 7

1- Hypertension in pheochromocytoma
2-Raynaud’s phenomenon
3- By intracavernous injection in treatment of impotence in males
4- Hypertensive crisi

Question 8

What is the side effect of Phentolamine ?

Answer 8

reflex tachycardia

Question 9

Give example of Selective a1 blockers ?

Answer 9

1- Alfuzosin
2- doxazosin
3- prazosin
4- tamsulosin
5- terazosin

Question 10

What is the Selective a1 blockers that Used in the treatment of chronic hypertension ?

Answer 10

1- Prazosin
2- doxazosin
3- terazosin

Question 11

What is the Selective a1 blockers used to treat urinary retention in men with benign prostatic hyperplasia ?

Answer 11

1- Alfuzosin

2- tamsulosin

Question 12

Why Tamsulosin is used in urinary retention in men with benign prostatic hyperplasia ?

Answer 12

because it is less selective for α1B receptors found in the blood vessels and more selective for α1A receptors in the prostate and bladder

Question 13

What is the uses of selective a1 blockers ?

Answer 13

elevated blood pressure

Question 14

Are not used as monotherapy ?

Answer 14

α1 antagonists

Question 15

What is the selective competitive α2-blocker ?

Answer 15

Yohimbine

Question 16

What is the uses of Yohimbine ( selective competitive α2-blocker ) ?

Answer 16

erectile dysfunction (male impotence).

Question 17

What is the alpha blockers that use to treatment of Pheochromocytoma ?

Answer 17

1- phenoxybenzamine

2- phentolamine

Question 18

What is the alpha Blocker that use to treating Hypertensive Emergencies ?

Answer 18

1- prazosin

2- terazosin

Question 19

What is the alpha Blocker that use to treating Chronic Hypertension ?

Answer 19

1- Prazosin
2- terazosin
3- doxazosin

Question 20

What is the alpha blocker that use to treating Raynaud’s phenomenon ?

Answer 20

1- prazosin

2- phenoxybenzamine.

Question 21

Benign Prostatic hyperplasia (BPH) ?

Answer 21

1- Tamsulosin

2- alfuzosin

Question 22

What is the Adverse effects of alpha- adrenergic antagonists ?

Answer 22

1- orthostatic hypotension
2- Inhibit ejaculation
3- nasal stuffiness
4- reflex tachycardia