Fluoroquinolones

Question 1

What is the Clinical uses of fluoroquinolones ?

Answer 1

1- Urinary tract infection
2- Typhoid fever
3- Osteomyelitis
4- Diabetic foot infections
5- peritonitis

Question 2

What is the Adverse effects of fluoroquinolones ?

Answer 2

1- QTc prolongation
2- Growing cartilage damage and arthropathy in
children
3- Tendinitis in adults

Question 3

What is the Adverse effects of fluoroquinolones in children ?

Answer 3

Growing cartilage damage and arthropathy

Question 4

What is the Adverse effects of fluoroquinolones in adults ?

Answer 4

Tendinitis

Question 5

What is the Contraindication of fluoroquinolones ?

Answer 5

1- QT interval prolongation
2- Severe hepatic functional impairment
3- during pregnancy and lactation
4- Renal function impairment (Moxifloxacin safe in renal imparment
5- Not recommended for age less than 18 years

Question 6

What is the drug that safe in renal imparment ?

Answer 6

Moxifloxacin

Question 7

What is the drug of fluoroquinolones that non-renal excretion; no dose adjustment required in renal functional impairment ?

Answer 7

Moxifloxacin

Question 8

What is the uses of fluoroquinolones ?

Answer 8

1- Urinary tract infection
2- Typhoid fever
3- Osteomyelitis
4- Diabetic foot infections
5- peritonitis
6- Drug of choice for prophylaxis and treatment of anthrax

Question 9

What is the drug of choice for prophylaxis and treatment of anthrax ?

Answer 9

fluoroquinolones

Question 10

What is the Adverse effects of fluoroquinolones ?

Answer 10

1- QTc prolongation
2-Growing cartilage damage and arthropathy in
children
3- Tendinitis in adults

Question 11

Ciprofloxacin is an ?

Answer 11

Inhibitor of CYP 1A2

Question 12

What is the Contraindication of fluoroquinolones ?

Answer 12

1- QT interval prolongation
2- Severe hepatic functional impairment
3- during pregnancy and lactation
4- Renal function impairment (Moxifloxacin safe in renal imparment
5- Not recommended for age less than 18 years

Question 13

What is the drug that safe in renal imparment ?

Answer 13

Moxifloxacin

Question 14

What is tha drug Not recommended for age less than 18 years ?

Answer 14

fluoroquinolones

Question 15

What is the drug should not be used in children less than 8 years of age ?

Answer 15

tetracyclines

Question 16

What is the Mechanismof action of Sulfonamides ?

Answer 16

Inhibits dihydropetroate synthase

Question 17

What is the uses of sulfonamides ?

Answer 17

1- Orally absorbable agents
2- Orally non- absorbable agents like sulfasalazine areuseful for the treatment of ulcerative colitis
3- Topical sulfonamides

Question 18

What is the drug is Orally non- absorbable taht useful for the treatment of ulcerative colitis ?

Answer 18

sulfasalazine

Question 19

What is the drug that used in Trachoma and bacterial conjuctivits ?

Answer 19

sulfacetamide

Question 20

What is the drug that used in Burn dressing ?

Answer 20

Silver sulfadiazine

Question 21

What is the Adverse effects of sulfonamides ?

Answer 21

1- Crystalluria
2- Steven Johnson syndrome
3- Hemolysis in patients with G6PD enzyme deficiency
4- Kernicterus

Question 22

What is the Mechanismof action of Trimethoprim ?

Answer 22

Inhibits dihydrofolate reductase

Question 23

What is the uses of trimethoprim ?

Answer 23

Pneumocystis pneumonia

Question 24

What is the drug of Pneumocystis pneumonia ?

Answer 24

trimethoprim

Question 25

Pyrimethamine and sulfadiazine are used in the | treatment of ?

Answer 25

toxoplasmosis

Question 26

What is the combination of the drugs that used for falciparum malaria ?

Answer 26

pyrimethamine with sulfadoxine

Question 27

What is the Mechanism of action of Sulfonamides ?

Answer 27

Inhibits dihydropetroate synthase

Question 28

What is the Mechanism of action of Trimethoprim ?

Answer 28

Inhibits dihydrofolate reductase