Lab Math Flashcards
1
Q
1 Kg
A
2.2 lbs
2
Q
1 in
A
2.54 cm
3
Q
1 kilo
A
1000 L, g, m
4
Q
10 deci
A
1 L, g, m
5
Q
100 centi
A
1 L, g, m
6
Q
1000 milli
A
1 L, g, m
7
Q
10*6 micro
A
1 L, g, m
8
Q
1000 micro
A
1 milli
9
Q
F*
A
9/5 C + 32
10
Q
C*
A
5/9 (F-32)
11
Q
%W/V
A
g per 100 mL of solution
12
Q
%W/W
A
g per 100 g solution
13
Q
%V/V
A
ml per 100 ml of solution
14
Q
Adjust concentration
A
C1 C1 = V2 C2
15
Q
Mean
A
average
16
Q
Median
A
Middle value
17
Q
Mode
A
Most frequent number
18
Q
Range
A
High number - low number
19
Q
Midrange
A
Low + High / 2
20
Q
Sensitivity
A
True positive or probability disease is present when test is positive TP FP
TP / FP + FN x 100 FN TN
21
Q
Specificity
A
True negative or probability that disease is not present when tested negative TP FP
TN / TN + FP x 100 FN TN
22
Q
Positive Predictive Value
A
TP / TP + FP x 100
23
Q
Negative Predictive Value
A
TN / TN + FN x 100
24
Q
HLA Relative risk
A
( TP x TN / FP x FN ) x 100
true / false
25
Relative Centrifugal Force
11.17 (r) (RPM/1000)^2
r = radius in cm
Or 28.38 (r) = radius in inches
26
Rotations per minute (RPM)
Square root (RCF/ 28.38 x r) x 1000
27
Half life IgG
21-28 days
28
Half life IgM
5 days
29
Half life of Factor VII
5 hours
30
Half life of Factor VIII
8-12 hours
31
Factor IX
20 hours
32
Total Blood Volume in adult
Female = 60 mL/Kg
Male = 66 mL/Kg
70-75 mL/Kg (Historical)
33
Total Blood Volume in Preterm infant
105 mL/Kg
34
Total Blood Volume in term infant
85- mL/Kg
35
1 unit of RBC will increase H/H
Hgb 1 g/dL
| HCT 3%
36
Yield of 1 random platelet
5.5 x 10^10 platelets
37
Yield of 1 apheresis platelet
3.0 x 10^11 platelets
38
1 random platelet should increase PLT count by
5-10,000 per unit
39
1 apheresis platelet should increase PLT count by
30-60,000 on adult
40
1 unit of FPP will increase clotting factors by
10% or 1 IU/mL
41
Factor VII in cryo
80 units
42
Fibrinogen in cryo
250 mg
43
VIII dose with cryo
( Plasma Volume (mL) x desired activity ) / 80
44
Fibrinogen dose with Cryo
( Plasma volume dL x desired volume ) / 250
45
Corrected Count Increament
```
( Post plt ct - pre plt ct ) x BSA (2) /
# of plts transfused
```
of plts = volume x yield x 10^3 (uL) = 10^11
Success > 7500 Refractory = <7500 in 2 transfusion
46
Platelet yeild
Final Concentration x Final volume /
| Original concentration x original volume x 100
47
HCT of Packed RBC
70%
48
% plasma removed in 1.0 volume exchange
65%
49
% plasma removed in 1.5 volume exchange
75%
50
% plasma removed in 2.0 volume exchange
88%
51
% plasma removed in 2.5 volume exchange
92%
52
% plasma removed in 3.0 volume exchange
96%
53
Anticoagulant 450 mL bag
63 mL
54
Volume drawn in 450 mL bag
405-495 mL
55
Anticoagulant in 500 mL bag
70 mL
56
Volume drawn in 500 mL bag
450-550 mL
57
450 mL bag low volume
300-404 ml
58
500 mL bag low volume
333-449 mL
59
IUT
Fetus wt in g x .14 x HCT increament / HCT of RBC
60
RHIG dosing
FMH = # fetal cells x 5000 / # maternal cells
Rhig = Volume of FMH / 30 ml plus 1 vial
61
RBC volume increase in neonate
10 mL/kg raises hct by 2-3 g/dL in a neonate
multiply by baby's weight in kg
additive RBC's with 65% HCT = 2 g/dL
Packed RBC's with 80% HCT = 3 g/dL
62
What % of transfused donor cells die each day?
1% of RBC will die each day
63
Calculate how much FFP to give to raise coag levels by X %?
```
PV x (% increase - % current) = mL of FFP
1 unit = 200-250 mL
```
64
How do you calculate platelet yield for random donor platelets?
PLT in plasma / (Volume of WB x Donor PLT Ct) x 100
Don't forget units!
PLT Count is # of PLT's x 1000/ul
PLT Count of 240 = 240,000/ul
65
How do you calculate F-VIII yield in Cryo?
F-VIII/mL x mL of final /
| F-VIII/mL x mL of original FFP x 100
66
How do you calculate Fibrinogen yield in Cryo?
Fib/mL x mL of final /
Fib/mL x mL of FFP x 100
*Fibrinogen is mg/dL so convert to mL
1 dL = 100 mL
67
Calculate how much FFP to give to a neonate
10-15 mL/kg will increase factors by 15-20%
68
Calculate how much PLT to give to a neonate
5-10 mL/kg will increase platelets by 50-100,000/uL
69
What is the specific gravity of whole blood?
1.053
70
How much anticoagulant is in whole blood?
Anticoagulant is 14 mL/100 mL or 0.14 mL per mL whole blood
71
What is the max Extra-corporal Volume
15% of total blood volume.
Example: 150 lb male patient = 68.2 kg x 66 ml/kg = 4500 mL TBV
4500 mL x 0.15 = 675 mL (max ECV)glg
72
How do you calculate % yield of deglycerolized RBC's?
(DRBC wt g x HCT /
| RBC wt g x HCT) x 100
73
How many mL in a pint?
473 mL
74
Calculate how much blood to drawn in donor less than 110 lbs?
```
Donor wt (Kg)/ 50 x 450 = (a) vol. to draw
a /100 x 14 = (b) amt of anticoagulant
63-b = amt to remove
```
75
What is the ration of anticoagulant to WB in CPD and CPDA-1 units?
1.4 to 10 ml
| or 14 to 100 ml
76
Calculate how many units to test to find compatible blood.
of units need / % negative
77
Calculate how many units will be compatible out of how many tested.
units tested x % negative
78
Calculate F-VIII concentrate dose.
PV x desired increment
