Lab Math Flashcards

1
Q

1 Kg

A

2.2 lbs

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2
Q

1 in

A

2.54 cm

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3
Q

1 kilo

A

1000 L, g, m

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4
Q

10 deci

A

1 L, g, m

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5
Q

100 centi

A

1 L, g, m

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6
Q

1000 milli

A

1 L, g, m

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7
Q

10*6 micro

A

1 L, g, m

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8
Q

1000 micro

A

1 milli

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9
Q

F*

A

9/5 C + 32

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10
Q

C*

A

5/9 (F-32)

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11
Q

%W/V

A

g per 100 mL of solution

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12
Q

%W/W

A

g per 100 g solution

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13
Q

%V/V

A

ml per 100 ml of solution

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14
Q

Adjust concentration

A

C1 C1 = V2 C2

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15
Q

Mean

A

average

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16
Q

Median

A

Middle value

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17
Q

Mode

A

Most frequent number

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18
Q

Range

A

High number - low number

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19
Q

Midrange

A

Low + High / 2

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20
Q

Sensitivity

A

True positive or probability disease is present when test is positive TP FP
TP / FP + FN x 100 FN TN

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21
Q

Specificity

A

True negative or probability that disease is not present when tested negative TP FP
TN / TN + FP x 100 FN TN

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22
Q

Positive Predictive Value

A

TP / TP + FP x 100

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23
Q

Negative Predictive Value

A

TN / TN + FN x 100

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24
Q

HLA Relative risk

A

( TP x TN / FP x FN ) x 100

true / false

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25
Q

Relative Centrifugal Force

A

11.17 (r) (RPM/1000)^2
r = radius in cm
Or 28.38 (r) = radius in inches

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26
Q

Rotations per minute (RPM)

A

Square root (RCF/ 28.38 x r) x 1000

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27
Q

Half life IgG

A

21-28 days

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28
Q

Half life IgM

A

5 days

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29
Q

Half life of Factor VII

A

5 hours

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30
Q

Half life of Factor VIII

A

8-12 hours

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31
Q

Factor IX

A

20 hours

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32
Q

Total Blood Volume in adult

A

Female = 60 mL/Kg
Male = 66 mL/Kg
70-75 mL/Kg (Historical)

33
Q

Total Blood Volume in Preterm infant

A

105 mL/Kg

34
Q

Total Blood Volume in term infant

A

85- mL/Kg

35
Q

1 unit of RBC will increase H/H

A

Hgb 1 g/dL

HCT 3%

36
Q

Yield of 1 random platelet

A

5.5 x 10^10 platelets

37
Q

Yield of 1 apheresis platelet

A

3.0 x 10^11 platelets

38
Q

1 random platelet should increase PLT count by

A

5-10,000 per unit

39
Q

1 apheresis platelet should increase PLT count by

A

30-60,000 on adult

40
Q

1 unit of FPP will increase clotting factors by

A

10% or 1 IU/mL

41
Q

Factor VII in cryo

A

80 units

42
Q

Fibrinogen in cryo

A

250 mg

43
Q

VIII dose with cryo

A

( Plasma Volume (mL) x desired activity ) / 80

44
Q

Fibrinogen dose with Cryo

A

( Plasma volume dL x desired volume ) / 250

45
Q

Corrected Count Increament

A
( Post plt ct - pre plt ct ) x BSA (2) /
# of plts transfused

of plts = volume x yield x 10^3 (uL) = 10^11

Success > 7500 Refractory = <7500 in 2 transfusion

46
Q

Platelet yeild

A

Final Concentration x Final volume /

Original concentration x original volume x 100

47
Q

HCT of Packed RBC

A

70%

48
Q

% plasma removed in 1.0 volume exchange

A

65%

49
Q

% plasma removed in 1.5 volume exchange

A

75%

50
Q

% plasma removed in 2.0 volume exchange

A

88%

51
Q

% plasma removed in 2.5 volume exchange

A

92%

52
Q

% plasma removed in 3.0 volume exchange

A

96%

53
Q

Anticoagulant 450 mL bag

A

63 mL

54
Q

Volume drawn in 450 mL bag

A

405-495 mL

55
Q

Anticoagulant in 500 mL bag

A

70 mL

56
Q

Volume drawn in 500 mL bag

A

450-550 mL

57
Q

450 mL bag low volume

A

300-404 ml

58
Q

500 mL bag low volume

A

333-449 mL

59
Q

IUT

A

Fetus wt in g x .14 x HCT increament / HCT of RBC

60
Q

RHIG dosing

A

FMH = # fetal cells x 5000 / # maternal cells

Rhig = Volume of FMH / 30 ml plus 1 vial

61
Q

RBC volume increase in neonate

A

10 mL/kg raises hct by 2-3 g/dL in a neonate
multiply by baby’s weight in kg
additive RBC’s with 65% HCT = 2 g/dL
Packed RBC’s with 80% HCT = 3 g/dL

62
Q

What % of transfused donor cells die each day?

A

1% of RBC will die each day

63
Q

Calculate how much FFP to give to raise coag levels by X %?

A
PV x (% increase - % current) = mL of FFP
1 unit = 200-250 mL
64
Q

How do you calculate platelet yield for random donor platelets?

A

PLT in plasma / (Volume of WB x Donor PLT Ct) x 100
Don’t forget units!
PLT Count is # of PLT’s x 1000/ul
PLT Count of 240 = 240,000/ul

65
Q

How do you calculate F-VIII yield in Cryo?

A

F-VIII/mL x mL of final /

F-VIII/mL x mL of original FFP x 100

66
Q

How do you calculate Fibrinogen yield in Cryo?

A

Fib/mL x mL of final /
Fib/mL x mL of FFP x 100
*Fibrinogen is mg/dL so convert to mL
1 dL = 100 mL

67
Q

Calculate how much FFP to give to a neonate

A

10-15 mL/kg will increase factors by 15-20%

68
Q

Calculate how much PLT to give to a neonate

A

5-10 mL/kg will increase platelets by 50-100,000/uL

69
Q

What is the specific gravity of whole blood?

A

1.053

70
Q

How much anticoagulant is in whole blood?

A

Anticoagulant is 14 mL/100 mL or 0.14 mL per mL whole blood

71
Q

What is the max Extra-corporal Volume

A

15% of total blood volume.

Example: 150 lb male patient = 68.2 kg x 66 ml/kg = 4500 mL TBV

4500 mL x 0.15 = 675 mL (max ECV)glg

72
Q

How do you calculate % yield of deglycerolized RBC’s?

A

(DRBC wt g x HCT /

RBC wt g x HCT) x 100

73
Q

How many mL in a pint?

A

473 mL

74
Q

Calculate how much blood to drawn in donor less than 110 lbs?

A
Donor wt (Kg)/ 50 x 450 = (a) vol. to draw
a /100 x 14 = (b) amt of anticoagulant
63-b = amt to remove
75
Q

What is the ration of anticoagulant to WB in CPD and CPDA-1 units?

A

1.4 to 10 ml

or 14 to 100 ml

76
Q

Calculate how many units to test to find compatible blood.

A

of units need / % negative

77
Q

Calculate how many units will be compatible out of how many tested.

A

units tested x % negative

78
Q

Calculate F-VIII concentrate dose.

A

PV x desired increment