Lab 1: Histology and Integumentary System Flashcards
define histology
the study of tissues
define tissues
a group a similarly structured cells that work together to accomplish a specific function
what are the four major tissue categories
- epithelial
- connective
- muscle
- nervous
how are specimens for histology prepared
- fixed/preserved
- thinly sectioned
- stained to improve contrast
what is the difference between acid stains and basic stains
- acid stains have negatively charged dyes
- basic stains have positively charged dyes
what do dyes bind to
oppositely charged macromolecules
define artifact
- a minor distortion in sectioned tissues that is only present due to the many steps needed to produce a histology slide
- should not be confused with the actual structure of preserved tissue
what does epithelial tissue do
- lines and covers organs, as well as their internal passageways
- creates boundaries between different environments
- forms glands
what are the strong intercellular connections between epithelial cells formed by
- tight junctions
- desmosomes
describe tight junctions
- connections between adjacent cells
- prevents fluid from moving between the cells
describe desmosomes
- connections between adjacent cells
- contains proteins
- allows cells to mechanically hold on to each other, providing mutual reinforcement
what are the functions of epithelia
- filtration
- absorption
- protection
- secretion
- excretion
- sensory reception
define the free/apical surface of epithelium
surface where cells are exposed to external environment or internal passageway/cavity
how do cells on the free/apical surface of epithelium obtain nutrients
diffusion of substances from connective tissue underlying the epithelia
define the basal lamina of epithelium
- where epithelium is attached to the body
- located between the epithelium and the connective tissue layer
what is the composition of basal lamina of epithilium
- glycoprotein secretions from the epithelial cells
- collagen fibers
what is the function of the basal lamina
- filter at the base of the epithelium
- forms a scaffold for wound repair
how are epithelia named
- shape
- number of cell layers
define simple epithelium
epithelium with only one layer of epithelial cells
what are the functions of simple epithelia
- diffusion
- absorption
- filtration
- secretion
what is the function of goblet cells
protect epithelia at the free surface by secreting mucus that coats the cell
describe the two different attachments on epithelial cells on the apical surface
- microvilli: increase surface area for absorption
- cilia: motile hair-like projections that sweep substances across the apical surface
define stratified epithelia
epithelium with more than one layer of epithelial cells
where is stratified epithelia found
- areas exposed to abrasion and friction
- body surface, upper digestive tract