L7: Spinal Degenerative Diseases Flashcards
Anatomical Overview of the vertebra
Pathology in Degenerative Disease of the Spine
Compression of the spinal Cord
Myelopathy
Most Common Myelopathy
Cervical spondylotic myelopathy (CSM)
Radiculopathy
Most Common Radicular Pain
sciatica - brachialgia
Stenosis
Spinal Degenerative Diseases
- Arthritis
Spinal Degenerative Diseases
- Bone Spurs
Symptoms of Spinal Degenerative Diseases
Red Flags of Spinal Degenerative Diseases
Red Flags of Spinal Degenerative Diseases
- Cauda Equina Syndrome
Red Flags of Spinal Degenerative Diseases
- Myelopathy
Red Flags of Spinal Degenerative Diseases
- Radiculopathy
Red Flags of Spinal Degenerative Diseases
- Others
RF for Spinal Degenerative Diseases
- Aging.
- Genetic predisposition.
- Smoking, diet, weight.
- Occupational (heavy lifting).
- Sedentary lifestyle.
Types of Spinal Degenerative Diseases
A) Disc bulge.
B) Annular tear.
C) Herniation.
Def of Disc Bulge
Normal IVD
Classification of Disc Bulge
Def of Annular Tear
Disruption of concentric collagenous fibers comprising the anulus fibrosus.
Types of Annular Tear
MRI of Annular Tear
Def of Disc Herniation
Types of Disc Herniation
Notes
Types of Disc Herniation
- Protrusion
The base of the herniated disc material is broader than the apex.
Types of Disc Herniation
- Extruded Disc Herniation
The base of the herniation is
narrower han the apex (toothpaste sign)
Types of Disc Herniation
- The Third Type?
Regions Affected by Disc Herniation
Epidemeology of Lumbar Disc Prolapse
Pathoanatomy of Lumbar Disc Prolapse
Prognosis of Lumbar Disc Prolapse
- 90% of patients will have improvement of symptoms within 3 months with nonoperative care
Reabsorbtion in Lumbar Disc Prolapse
- def
- Mechanism
- Type
Classification of Lumbar Disc Prolapse
- According to Location
- According to Anatomy
Classification of Lumbar Disc Prolapse
- Acoording to location
Classification of Lumbar Disc Prolapse
- Central Prolapse
- Often associated with back pain only
- May present with Cauda equina syndrome (surgical emergency)
Classification of Lumbar Disc Prolapse
- Posterolateral Prolapse (Paracentral)
Classification of Lumbar Disc Prolapse
- Foraminal Prolapse (Far Lateral, Extraforaminal)
Classification of Lumbar Disc Prolapse
- Axillary Prolapse
Can affect Both exiting and descending nerve roots
Classification of Lumbar Disc Prolapse
- According to Anatomy
Dx of Lumbar Disc Prolapse
- Physical Examination
- Imaging
- Neurophysiological
Dx of Lumbar Disc Prolapse
- Physical Examination
- Neurological exam (sensory-motor-reflexes).
- Provocative tests
Dx of Lumbar Disc Prolapse
- Imaging
Imaging in Lumbar Disc Prolapse
- MRI
MRI (Investigation of choice)
- Most accurate assessment of lumbar spine area
- There is a 29% prevalence of disc herniation in asymtomatic individuals.
Imaging in Lumbar Disc Prolapse
- CT
…
Imaging in Lumbar Disc Prolapse
- X-ray
traction spurs & disc space narrowing
Dx in Lumbar Disc Prolapse
- Neurophysiological
EMG
Symptoms of Lumbar Disc Prolapse
Def of Cauda Equina Syndrome
Serious neurologic condition in which damage to the cauda equina
Pathophysiology of Cauda Equina Syndrome
- Loss of function of the lumbar plexus (nerve roots) of the spinal canal below the termination (conus medullaris) of the spinal cord (Lower motor neuron lesion
Symptoms of Cauda Equina Syndrome
Lumbar Disc Prolapse
- L4
Lumbar Disc Prolapse
- L5
Lumbar Disc Prolapse
- S1
Provocative Tests in Lumbar Disc Prolapse
Provocative Tests in Lumbar Disc Prolapse
- Straight Leg Raise
Provocative Tests in Lumbar Disc Prolapse
- Contralateral SLR
Crossed straight leg raise is less sensitive but more specifid
Provocative Tests in Lumbar Disc Prolapse
- Lassegue Sign
SLR aggravated byforced ankle dorsiflexion
Provocative Tests in Lumbar Disc Prolapse
- Bowstring Sign
SLR aggravated by compression on popliteal fossa
Provocative Tests in Lumbar Disc Prolapse
- Kernig Test
Pain reproduced with neck flexion, hip flexion, and leg extension
Provocative Tests in Lumbar Disc Prolapse
- Nafziger Test
- Pain reproduced by foughing
- Instigated by lying patient supine & applying pressure on neck veins
Provocative Tests in Lumbar Disc Prolapse
- Milgram Test
- Pain reproduced with straight leg elevation for 3o seconds in the supine)position
DDx of Lumbar Disc Prolapse
Prognosis of Lumbar Disc Prolapse
Management of Lumbar Disc Prolapse
1) Conservative (Non operative)
2) Selective nerve root corticosteroid injections
3) Surgical
Management of Lumbar Disc Prolapse
- Conservative
Conservative Management of Lumbar Disc Prolapse
- Indications
1) First line of treatment for most patients with disc herniation
2) 90% improve without surgery
Conservative Management of Lumbar Disc Prolapse
- Methods
Selective Nerve Root Corticosteroids Injections of Lumbar Disc Prolapse
Selective Nerve Root Corticosteroids Injections of Lumbar Disc Prolapse
- Indication
Second line of treatment if therapy and medications fail
Selective Nerve Root Corticosteroids Injections of Lumbar Disc Prolapse
- Methods
- Epidural
- Selective nerve block
Selective Nerve Root Corticosteroids Injections of Lumbar Disc Prolapse
- Outcome
- Leads to long lasting improvement in 50% compared to ~90% with surgery)
- Results best in patients with extruded discs is opposed to contained
Surgical TTT of Lumbar Disc Prolapse
Surgical TTT of Lumbar Disc Prolapse
- Indications
Surgical TTT of Lumbar Disc Prolapse
- Methods
Complications of Surgical TTT of Lumbar Disc Prolapse
Comlications of Lumbar Disc Prolapse
- dural Tear
- If have tear at time of surgery then perform water-tight repair
- Has not been shown to adversely affect long term outcomes
Comlications of Lumbar Disc Prolapse
- Recurrent HNP
- Can treat nonoperatively initially - revision rate a 8-yr-FU is 15%
- Outcomes for revision discectomy have been shown to be as good as for primary discectomy
Comlications of Lumbar Disc Prolapse
- Chronic Low Back Pain
- Not completely understood but central sensitization may be a factor
- Amplification of neural signaling within the central nervous system (CNS) that elicits pain
Comlications of Lumbar Disc Prolapse
- Vascular Catastrophe
- Caused by breaking through anterior annulus and injuring vena cava/aorta
Comlications of Lumbar Disc Prolapse
- Instability
….
Comlications of Lumbar Disc Prolapse
- Discitis
……
Epidemeology of Cervical Disc Prolapse
- Most often between (C5/6) and (C6/7).
- The nerves of the cervical plexus and brachial plexus can be affected
Symptoms of Cervical Disc Prolapse
Symptoms of Cervical Disc Prolapse
- Sites Affected
1) Back of the skull
2) Neck
3) Shoulder girdle
4) Scapula
5) Arm and hand.
Symptoms of Cervical Disc Prolapse
- Examples
1) Pain (neck, shoulder, arm, hand).
2) Radiculopathy.
3) Numbness.
4) Muscle weakness.
5) Paresthesia.
6) Severe cases: myelopathy + sphincteric disturbance (urinary incontinence and loss of bowel control).
Symptoms of Cervical Disc Prolapse
- C4/C5
Symptoms of Cervical Disc Prolapse
- C5/C6
Symptoms of Cervical Disc Prolapse
- C6/C7
Symptoms of Cervical Disc Prolapse
- C7/T1
Dx of Cervical Disc Prolapse
- Ex
- Radiology
Dx of Cervical Disc Prolapse
- Ex
Dx of Cervical Disc Prolapse
- Cervical Compression Test & (Spurling’s test)
Dx of Cervical Disc Prolapse
- Lhermitte Sign
Feeling of electrical shock with patient neck flexion
Dx of Cervical Disc Prolapse
- Hoffman Sign
Dx of Cervical Disc Prolapse
- rads
TTT of Cervical Disc Prolapse
TTT of Cervical Disc Prolapse
- Conservative
- Medications (NSAID).
- Physical therapy and exercise.
- Steroid injection.
TTT of Cervical Disc Prolapse
- Surgery
Def of Spinal Canal Stenosis
Abnormal narrowing (stenosis) of spinal canal that may occur in any of the regions of the spine → restriction to the spinal canal → neurological deficit
Symptoms of Spinal Canal Stenosis
1) Pain
2) Numbness, paraesthesia
3) Loss of motor control.
Incidence of Lumbar Canal Stenosis
- Most common reason for lumbar spine surgery in pts > 65 yrs old
- seen in 20-25%
Lumbar Canal Stenosis
- Sex
- Age
- Sex: Slightly more common in males (D5:1)
- Age: Average age at presentation 5 65 years old
Location of Lumbar Canal Stenosis
Most commonly occurs at L4-5 (91%)
Risk Factors for Lumbar Canal Stenosis
1) Caucasian race
2) Increased BMI
3) Congenital spine anomalies (20%)
4) Failure of posterior elements to develop, short pedicles and laminae
Classification (Types) of Lumbar Canal Stenosis
1) Central stenosis
2) Lateral recess stenosis
3) Foramen stenosis
4) Extraforaminal Stenosis
Symptoms of Lumbar Canal Stenosis
Symptoms of Lumbar Canal Stenosis
- Neurogenic Claudication
Signs of Lumbar Canal Stenosis
Signs of Lumbar Canal Stenosis
- Kemp Sign
- Unilateral radicular pain from foraminal stenosis
- Worse by back extension
Signs of Lumbar Canal Stenosis
- SLR
Usually, negative
Signs of Lumbar Canal Stenosis
- Valsalva
- Radicular pain not worsened by Valsalva as is the case with a herniated disc
Signs of Lumbar Canal Stenosis
- Neuro Exam
- Patients may have no focal deficits
- cAs exam often takes place with patient seated and symptoms may be reproducible or exacerbated only with lumbar extension or ambulation
Radiology in Lumbar Canal Stenosis
Management of Lumbar Canal Stenosis
- Non-Operative
- Operative
Management of Lumbar Canal Stenosis
- Non-Operative
Non-Operative Management of Lumbar Canal Stenosis
- Modalities
Oral medications, physical therapy, and corticosteroid injections
Non-Operative Management of Lumbar Canal Stenosis
- Indications
First line of treatmen
Non-Operative Management of Lumbar Canal Stenosis
- Modalities (Explained)
1) NSAIDS, physical therapy, weight loss and bracing:
- Preoperative opioid use associated with prolonged hospital stays and increased postoperative pain.
2) Steroid injections (epidural and transforminal):
- Found to be effective and may obviate the need for surgery
Surgical Management of Lumbar Canal Stenosis
Surgical Management of Lumbar Canal Stenosis
- Wide PTP Decompression
Surgical Management of Lumbar Canal Stenosis
- Wide PTP Decompression with instrumented fusion
Def of Spondylosis
- Broad term meaning degeneration of the spinal column from any cause.
- In the more narrow sense it refers to spinal osteoarthritis, age-related wear and tear of the spinal column (most common cause of spondylosis)
Spondylotic osteoarthritis mainly affects ……..
- Vertebral bodies.
- Neural foramina
- Facet joints (facet syndrome).
Spinal Instability
…
Def of Spondylolishthesis
An anterior displacement of a vertebra relative to the vertebra below.
Retrolisthesis
“the reverse” the superior vertebra slips posterior to that below.
Grading of Spondylolishthesis
Etiological Classification of Spondylolishthesis
Etiological Classification of Spondylolishthesis
- Dysplastic
Congenital dysplasia of the articular processes.
Etiological Classification of Spondylolishthesis
- Isthmic
Defect in the pars articularis.
Etiological Classification of Spondylolishthesis
- Degenerative
Degenerative changes in the facet joints.
Etiological Classification of Spondylolishthesis
- Traumatic
Fracture of the neural arch other than the pars articularis.
Etiological Classification of Spondylolishthesis
- Pathological
Weakening of the neural arch due to disorders of the bone.
Etiological Classification of Spondylolishthesis
- Iatrogenic
- Excessive removal of bone following spinal decompression.
Isthmic Spondylolishthesis
- AKA
Spondylolytic Spondylolisthesis
Isthmic Spondylolishthesis
- Incidence
Most common form
Isthmic Spondylolishthesis
- Pathology
A bilateral defect in the pars interarticularis is present
What is Pars interarticularis (AKA Isthmus)?
- Pars interarticularis (AKA Isthmus) is the part of the neural arch that joins the superior and inferior articular processes
Degenerative Spondoylolishthesis
…
Degenerative Spondoylolishthesis
- Description
A lumbar spondylolisthesis without a defect in the pars
Degenerative Spondoylolishthesis
- Level
Most common is L4-L5
Degenerative Spondoylolishthesis
- INVx
Dynamic radiographs: Flexion-Extension X-rays
CP of Spondoylolishthesis
CP of Spondoylolishthesis
- Axial Back Pain
- Most common presentation.
- Pain usually has a long history with periodic episodes that vary in intensity and duration.
CP of Spondoylolishthesis
- Leg Pain
Usually a L5 radiculopathy (foraminal stenosis at the L5-S1 level).
CP of Spondoylolishthesis
- Neurogenic Claudication
- Caused by spinal stenosis.
- Characterized by buttock and leg pain worse with walking.
- N.B: Symptoms of neurogenic claudication rare because these slips rarely progress beyond Grade Il
CP of Spondoylolishthesis
- Cauda Equina Syndrome
Rare because these slips rarely progress beyond Grade II.
CP of Spondoylolishthesis
- L5 Radiculopathy
Physical Exam: Ankle dorsiflexion and EHL veakness
Management of Spondoylolishthesis
- Non Operatice
- Operative
Management of Spondoylolishthesis
- Non-Operative
Non-Operative Management of Spondoylolishthesis
- Examples
Oral medications, lifestyle modifications, therapy
Non-Operative Management of Spondoylolishthesis
- Techniques
- Activity restriction.
- NSAID.
- Role of injections unclear.
- Bracing may be beneficial especially in the acute phase.
Non-Operative Management of Spondoylolishthesis
- Indications
Most patients can be treated nonoperatively
Operative Management of Spondoylolishthesis
- L5-S1 Decompression & Instrumented Fusion +- Reduction
- L4-S1 Decompression & Instrumented Fusion +- Reduction
- ALIF
Operative Management of Spondoylolishthesis
- L5-S1 Decompression & Instrumented Fusion +- Reduction
Operative Management of Spondoylolishthesis
- L5-S1 Decompression & Instrumented Fusion +- Reduction (Indications)
Operative Management of Spondoylolishthesis
- L5-S1 Decompression & Instrumented Fusion +- Reduction (Reduction)
Operative Management of Spondoylolishthesis
- L4-S1 Decompression & Instrumented Fusion +- Reduction
Operative Management of Spondoylolishthesis
- L4-S1 Decompression & Instrumented Fusion +- Reduction (Indications)
Operative Management of Spondoylolishthesis
- ALIF
Operative Management of Spondoylolishthesis
- ALIF (Indications)
Operative Management of Spondoylolishthesis
- ALIF (Outcomes)