L5: Prostate Cancer Flashcards

1
Q

Anatomical Overview of Prostate

A
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2
Q

Epidemeology of Prostate Cancer

A
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3
Q

Genitourinary Cancers

  • % of solid tumors
A
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4
Q

Genitourinary Cancers

  • Incidence of Mortality in each
A
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5
Q

RF for Prostate Cancer

A
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6
Q

RF for Prostate Cancer

  • Non modifiable
A
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7
Q

Non Modifiable RF for Prostate Cancer

  • Age
A
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8
Q

Non Modifiable RF for Prostate Cancer

  • Race
A
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9
Q

Non Modifiable RF for Prostate Cancer

  • Family Hx
A
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10
Q

Non Modifiable RF for Prostate Cancer

  • Nationality
A
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11
Q

Non Modifiable RF for Prostate Cancer

  • Genetics
A
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12
Q

Modifiable RF for Prostate Cancer

A
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13
Q

Precancerous Lesions in Prostate Cancer

A
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14
Q

Precancerous Lesions in Prostate Cancer

  • PIN
A
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15
Q

Precancerous Lesions in Prostate Cancer

  • PIA
A
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16
Q

Classification & Sites of Prostate Cancer

A
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17
Q

Classification & Sites of Prostate Cancer

  • Epithelial Tumors
A
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18
Q

Classification & Sites of Prostate Cancer

  • Stromal Tumors
A
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19
Q

Classification & Sites of Prostate Cancer

  • Secondary Cause
A
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20
Q

Classification & Sites of Prostate Cancer

  • Most Common Type
A
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21
Q

Microscopic Examination of Prostate Cancer

A
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22
Q

Microscopic Examination of Prostate Cancer

  • Based On
A
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23
Q

Microscopic Examination of Prostate Cancer

  • Gleason Grading System
A
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24
Q

Staging of Prostate Cancer

A
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25
Q

Staging of Prostate Cancer

  • T
A
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26
Q

Staging of Prostate Cancer

  • N
A
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27
Q

Staging of Prostate Cancer

  • M
A
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28
Q

Spread of Prostate Cancer

A
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29
Q

Spread of Prostate Cancer

  • Local
A
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30
Q

Spread of Prostate Cancer

  • Lymphatic
A
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31
Q

Spread of Prostate Cancer

  • Hematogenous
A
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32
Q

Spread of Prostate Cancer

  • Most common Site of Hematogenous Mets
A
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33
Q

Dx of Prostate Cancer

A
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34
Q

Dx of Prostate Cancer

  • CP
A
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35
Q

CP of Prostate Cancer

  • Asymptomatic
A
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36
Q

CP of Prostate Cancer

  • Manifest
A
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37
Q

CP of Prostate Cancer

  • Complications
A
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38
Q

CP of Prostate Cancer

  • Metastasis
A
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39
Q

Screening for Prostate Cancer

  • Why?
  • For Whom?
  • How?
A
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40
Q

DRE in Prostate Cancer

A
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41
Q

Findings in DRE in Prostate Cancer

A
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42
Q

Size in DRE in Prostate Cancer

A
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43
Q

Accuracy of DRE in Prostate Cancer

A
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44
Q

False Positive in DRE in Prostate Cancer

A
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45
Q

False Negative in DRE in Prostate Cancer

A
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46
Q

INVx for Prostate Cancer

A
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47
Q

INVx for Prostate Cancer

  • PSA
A
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48
Q

Def of PSA

A
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49
Q

Normal Values of PSA

A
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50
Q

levels of PSA Over Time

  • Normal
  • BPH
  • Prostate Cancer
A
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51
Q

Factors increasing PSA

A
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52
Q

Factors Decreaseing PSA

A
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53
Q

Importance of PSA

A
54
Q

Importance of PSA

  • Diagnosis
A
55
Q

Importance of PSA

  • Staging & TTT Decision
A
56
Q

Importance of PSA

  • Follow Up
A
57
Q

Follow Up by PSA

A
58
Q

Follow Up by PSA

  • Surgery
A
59
Q

Follow Up by PSA

  • radiotherapy
A
60
Q

Follow Up by PSA

  • Metastatic Cancer
A
61
Q

Other Tumor Markers for Prostate Cancer

A
62
Q

TRUS in Prostate Cancer

A
63
Q

Value of TRUS in Prostate Cancer

A
64
Q

False Positive in TRUS in Prostate Cancer

A
65
Q

False Negative in TRUS in Prostate Cancer

A
66
Q

Types of Tissue Biopsy in Prostate Cx

A
67
Q

Indications of Tissue Biopsy in Prostate Cx

A
68
Q

Indications of Tissue Biopsy in Prostate Cx

  • Absolute
A
69
Q

Indications of Tissue Biopsy in Prostate Cx

  • Relative Indications
A
70
Q

Interpretation of Age-Adjusted PSA

A
71
Q

Def of PSA Velocity

A
72
Q

Interpretation of PSA Velocity

A
73
Q

Rationale of Free PSA

A
74
Q

Interpretation of Free PSA

A
75
Q

Rationale of PSA Density

A
76
Q

Def of PSA Density

A
77
Q

Interpertation of PSA Density

A
78
Q

Imaging in Prostate Cx

A
79
Q

Imaging in Prostate Cx

  • CT, MRI
A
80
Q

Indications of CT,MRI in Prostate Cx

A
81
Q

Role of Pelvic Lymphadenectomy in Prostate Cx

A
82
Q

Bone Scan in Prostate Cx

A
83
Q

Indications of Bone Scan in Prostate Cx

A
84
Q

Why is Bone Scan Mandatory in Prostate Cx?

A
85
Q

Methods of Therapy in Organ-Confined Prostate Cx

A
86
Q

Methods of Therapy in Prostate Cx

  • T1a
A
87
Q

Methods of Therapy in Prostate Cx

  • T1b, T1c, T2
A
88
Q

Methods of Therapy in Prostate Cx

  • T3
A
89
Q

Methods of Therapy in Prostate Cx

  • Metastatic
A
90
Q

Methods of Therapy in Prostate Cx

  • Low Risk
A
91
Q

Methods of Therapy in Prostate Cx

  • Moderat Risk
A
92
Q

Methods of Therapy in Prostate Cx

  • High Risk
A
93
Q

Methods of TTT of Prosate Cx

A
94
Q

Methods of TTT of Prosate Cx

  • Watchful Waiting
A
95
Q

Methods of TTT of Prosate Cx

  • Radical Prostatectomy
A
96
Q

Methods of TTT of Prosate Cx

  • Radiotherapy
A
97
Q

Methods of TTT of Prosate Cx

  • Depend on
A
98
Q

Methods of Watchful Waiting in Prostate Cx

A
99
Q

Indications of Watchful Waiting in Prostate Cx

A
100
Q

CI of Watchful Waiting in Prostate Cx

A
101
Q

Advantages of Watchful Waiting in Prostate Cx

A
102
Q

Disadvantages of Watchful Waiting in Prostate Cx

A
103
Q

Watchful Waiting in Prostate Cx

  • NB
A
104
Q

Indications of Radical Prostatectomy in Prostate Cx

A
105
Q

CI of Radical Prostatectomy in Prostate Cx

A
106
Q

Advanatages of Radical Prostatectomy in Prostate Cx

A
107
Q

Disadvantages of Radical Prostatectomy in Prostate Cx

A
108
Q

Method of External Radiation in prostate Cx

A
109
Q

Indications of External Radiation in prostate Cx

A
110
Q

CI in External Radiation in prostate Cx

A
111
Q

Advanatges of External Radiation in prostate Cx

A
112
Q

Disadvantages of External Radiation in prostate Cx

A
113
Q

External Radiation in prostate Cx

  • NB (Techniques)
A
114
Q

Indications of Brachytherapy in Prostate Cx

A
115
Q

CI of Brachytherapy in Prostate Cx

A
116
Q

Advantages of Brachytherapy in Prostate Cx

A
117
Q

Disadvantages of Brachytherapy in Prostate Cx

A
118
Q

TTT options in Symptomatic Metastatic Disease

A
119
Q

Indications of Hormonal TTT of Prostate Cx

A
120
Q

Pathophysiology of Hormonal TTT of Prostate Cx

A
121
Q

Lines of Hormonal TTT of Prostate Cx

A
122
Q

Results of Androgen Removal in TTT of Prostate Cx

A
123
Q

Medications used in Hormonal TTT of Prostate Cx

A
124
Q

Hormonal TTT of Prostate Cx

  • LHRH Analogues
A
125
Q

Hormonal TTT of Prostate Cx

  • Antiandrogenic
A
126
Q

Finasteride & bicalutamide as primary hormonal therapy in advanced adenocarcinoma of the prostate

A
127
Q

Significance of HRPC

A
128
Q

TTT of HRPC

A
129
Q

TTT of HRPC

  • Cytotoxic Chemo
A
130
Q

TTT of HRPC

  • Bisphosphonate
A