L4 epithelium Flashcards

1
Q

what is meant by cell polarity

A

each surface different and specialised for a different function eg apical vs basolateral

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2
Q

what are the 3 cell domains

A

apical
lateral
basal

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3
Q

specialisations of the apical surface

A

glycocalyx coating
cilia
microvilli (glycocalyx coating)

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4
Q

what regions of the apical surface will have no glycocalyx layer?

A

cilia regions

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5
Q

how does the glycocalyx layer appear in a histological image

A

orange - brown band

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6
Q

function of glycocalyx in epithelial cells?

A
  1. cell recognition
  2. intercellular adhesion
  3. cell communication
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7
Q

what can be found in the glycocalyx

A

glycolipids and glycoproteins

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8
Q

function of glycocalyx in endothelial cells

A

regulates permeability

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9
Q

where are cilia found and how do they appear

A

hair like

trachea, uterine tube

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10
Q

describe appearance of microvilli

A

tall closely packed projections

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11
Q

microvilli function and where theyre found

A

absorption

SI

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12
Q

how can determine cilia from microvilli

A

cilia longer and thinner and are not surrounded by glycocalyx

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13
Q

basal lamina function

A

cell adhesion interface

permeability barrier

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14
Q

lateral region function

A

cell to cell interactions

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15
Q

what defines ‘simple’ epithelium

A

single cell layer

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16
Q

what defines ‘stratified’ epithelium

A

two or more layers of cells

17
Q

where is simple epithelia likely to be found

A

absorption/diffusion/secretion surfaces
eg
lungs
SI

18
Q

where is stratified epithelium likely to be found

A

sites prone to mechanical abrasion
pharynx
oesophagus
cervix

19
Q

describe squamos cells

A

look flattened

wider than they are tall

20
Q

describe cuboidal cells

A

cube shape

same width and height

21
Q

describe columnar cells

A

like rectangles

higher than they are wide

22
Q

where will simple squamos epithelia usually be found

A

lungs

capillaries

23
Q

describe features of pseudostratified epithelium

A
appears stratified (more than one cell thick)
all cells sit on basement membrane but not all reach surface
24
Q

where is the nuclei of pseudostratified epithelium usually located

A

towards basal end

25
Q

can cilia be present on stratified epithelium?

A

no

26
Q

can cilia be present on pseudostratified epithelium

A

yes

27
Q

where can pseudo stratified epithelium only be found found

A

conducting zone of respiratory tract

respiratory epithelium

28
Q

what is transitional epithelium

A

a type of stratified epithelium where:
basal layer roughly cuboidal
apical cells are dome shaped

29
Q

what is a feature of apical cells of transitional epithelium

A

dome shaped

may be multinucleate

30
Q

what type is endothelium?

A

simple squamous

31
Q

functions of epithelia

A

protective barrier
selective barrier
gland formations
absorption

32
Q

what type of cells are goblet cells

A

modified columnar

33
Q

what epithelium mediates gas exchange

A

simple squamous

34
Q

what epithelium mediates absorption & secretion

A

simple usually columnar

35
Q

what epithelium mediates filtration

A

simple

36
Q

what epithelium mediates reabsorption

A

simple cuboidal

37
Q

what epithelium lines organs which are subject to large changes in volume?

A

transitional

38
Q

what epithelium lines trachea

A

Pseudostratified columnar