L4 epithelium Flashcards
what is meant by cell polarity
each surface different and specialised for a different function eg apical vs basolateral
what are the 3 cell domains
apical
lateral
basal
specialisations of the apical surface
glycocalyx coating
cilia
microvilli (glycocalyx coating)
what regions of the apical surface will have no glycocalyx layer?
cilia regions
how does the glycocalyx layer appear in a histological image
orange - brown band
function of glycocalyx in epithelial cells?
- cell recognition
- intercellular adhesion
- cell communication
what can be found in the glycocalyx
glycolipids and glycoproteins
function of glycocalyx in endothelial cells
regulates permeability
where are cilia found and how do they appear
hair like
trachea, uterine tube
describe appearance of microvilli
tall closely packed projections
microvilli function and where theyre found
absorption
SI
how can determine cilia from microvilli
cilia longer and thinner and are not surrounded by glycocalyx
basal lamina function
cell adhesion interface
permeability barrier
lateral region function
cell to cell interactions
what defines ‘simple’ epithelium
single cell layer
what defines ‘stratified’ epithelium
two or more layers of cells
where is simple epithelia likely to be found
absorption/diffusion/secretion surfaces
eg
lungs
SI
where is stratified epithelium likely to be found
sites prone to mechanical abrasion
pharynx
oesophagus
cervix
describe squamos cells
look flattened
wider than they are tall
describe cuboidal cells
cube shape
same width and height
describe columnar cells
like rectangles
higher than they are wide
where will simple squamos epithelia usually be found
lungs
capillaries
describe features of pseudostratified epithelium
appears stratified (more than one cell thick) all cells sit on basement membrane but not all reach surface
where is the nuclei of pseudostratified epithelium usually located
towards basal end
can cilia be present on stratified epithelium?
no
can cilia be present on pseudostratified epithelium
yes
where can pseudo stratified epithelium only be found found
conducting zone of respiratory tract
respiratory epithelium
what is transitional epithelium
a type of stratified epithelium where:
basal layer roughly cuboidal
apical cells are dome shaped
what is a feature of apical cells of transitional epithelium
dome shaped
may be multinucleate
what type is endothelium?
simple squamous
functions of epithelia
protective barrier
selective barrier
gland formations
absorption
what type of cells are goblet cells
modified columnar
what epithelium mediates gas exchange
simple squamous
what epithelium mediates absorption & secretion
simple usually columnar
what epithelium mediates filtration
simple
what epithelium mediates reabsorption
simple cuboidal
what epithelium lines organs which are subject to large changes in volume?
transitional
what epithelium lines trachea
Pseudostratified columnar