L12 - respiratory anatomy and histology Flashcards

1
Q

what cells line alveoli

A

type 1 and type 2 pneumocytes

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2
Q

type 1 pneumocyte function

A

involved in gas exchange - line alveoli

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3
Q

what epithelia are type 1 pneumocytes

A

squamous

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4
Q

what epithelia are type 2 pneumocytes

A

cuboidal

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5
Q

what type of pneumocyte is most abundant

A

1

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6
Q

how are type 1 pneumocytes connected to eachother

A

tight junctions

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7
Q

type 2 pneumocyte function

A

produce surfactant

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8
Q

are type 1 or 2 pneumocytes bigger

A

2

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9
Q

what two things increase thoracic volume

A

diaphragm

ribs

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10
Q

explain inspiration at rest

A
  1. diaphragm contracts and flattens
  2. abdominals relax
  3. external intercostals contract pulling ribs up and out

increases thoracic vol, decreases pressure, air in

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11
Q

explain expiration at rest

A
  1. diaphragm relaxes into dome shape

2. passive recoil of lungs expels air

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12
Q

explain inspiration during exercise

A
  1. forceful diaphragm contraction
  2. accessory inspiratory muscles contract
  3. further outward expansion
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13
Q

what are the accessory muscles

A

external intercostals
scalenes
etc

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14
Q

explain expiration during exercise

A
  1. abdominals and diaphragm contract - rapid collapse of lungs
  2. internal intercostals contract pulling ribs down
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15
Q

name the two pleural membranes

A
parietal (outer)
visceral pleura (inner - covers lungs)
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16
Q

what is the function of the fluid filled space between the pleural membranes

A
  1. allows membranes to move across eachother

2. cohesion - lungs adhere to thoracic cavity and expand with thorax

17
Q

what does upper respiratory tract include

A

nasal cavity to larynx

18
Q

what does lower respiratory tract include

A

trachea - alveoli

19
Q

what is the conducting zone

A

trachea - terminal bronchiole

where no gas exchange takes place

20
Q

what lines the conducting zone

A

respiratory epithelium

pseudostratified columnar, ciliated , goblet cells

21
Q

what is the respiratory zone

A

below terminal bronchioles (respiratory bronchiole, alveoli)

where gas exchange takes place

22
Q

how does epithelium differ from conducting zone to respiratory zone

A

changes to cuboidal
goblet cells replaced by club cells
no cilia

23
Q

function of club cells

A

release surfactant

act as stem cells for other epithelial cells in bronchioles