L28 Respiratory viruses Flashcards
Influenza
Family
Genome
Virion
Orthomyxoviridae
(-)ssRNA segmented
Enveloped
Adenovirus
Family
Genome
Virion
Adenovirdae
dsDNA
Non-enveloped
Rhinovirus
Family
Genome
Virion
Piconavirus
(+)ssRNA
Non-enveloped
Most common influenza
Type A
Influenza type A genome
8 Segments
Most severe influenza
Type A
Influenza proteins and function
HA: Hemagglutinin: cell attachment
NA: Neuraminidase: budding and release
Major determinant for Avian vs Human
HA
Influenza replication
Nucleus (Exception)
Type A reservoir
Birds
Influenza transmission
Aerosol droplets
Influenze incubation time
1-4 days
Contagious day before symptoms
Flu symptoms
fever
malaise
nonproductive cough
Current flu stains
H3N2, H1N1
Flu complications
Viral pneumonia
Bacterioa pneumonia
Reye syndoms
Flu vaccine
Live attenuated
Most common studied adenoviruses
2 and 5
Adenovirus entry
Receptor mediated endocytosis
pH triggered disassembly
Move to nucleus
Adenovirus phases
Immediate early
Early
Late
adenovirus replication occurs during
S phase
Adenovirus is similar to ______ processes
Onceogenic
Adenovirus symptoms
Nasal congestion
inflammation
cough
(like common cold)
Serious adenovirus symptoms
population
Acute respiratory disease
Military recruits
Age for respiratory infections from adenovirus
under 14
