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Micro 2 > L28 Respiratory viruses > Flashcards

L28 Respiratory viruses Flashcards

1
Q

Influenza
Family
Genome
Virion

A

Orthomyxoviridae
(-)ssRNA segmented
Enveloped

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2
Q

Adenovirus
Family
Genome
Virion

A

Adenovirdae
dsDNA
Non-enveloped

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3
Q

Rhinovirus
Family
Genome
Virion

A

Piconavirus
(+)ssRNA
Non-enveloped

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4
Q

Most common influenza

A

Type A

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5
Q

Influenza type A genome

A

8 Segments

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6
Q

Most severe influenza

A

Type A

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7
Q

Influenza proteins and function

A

HA: Hemagglutinin: cell attachment
NA: Neuraminidase: budding and release

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8
Q

Major determinant for Avian vs Human

A

HA

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9
Q

Influenza replication

A

Nucleus (Exception)

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10
Q

Type A reservoir

A

Birds

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11
Q

Influenza transmission

A

Aerosol droplets

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12
Q

Influenze incubation time

A

1-4 days

Contagious day before symptoms

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13
Q

Flu symptoms

A

fever
malaise
nonproductive cough

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14
Q

Current flu stains

A

H3N2, H1N1

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15
Q

Flu complications

A

Viral pneumonia
Bacterioa pneumonia
Reye syndoms

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16
Q

Flu vaccine

A

Live attenuated

17
Q

Most common studied adenoviruses

A

2 and 5

18
Q

Adenovirus entry

A

Receptor mediated endocytosis
pH triggered disassembly
Move to nucleus

19
Q

Adenovirus phases

A

Immediate early
Early
Late

20
Q

adenovirus replication occurs during

A

S phase

21
Q

Adenovirus is similar to ______ processes

A

Onceogenic

22
Q

Adenovirus symptoms

A

Nasal congestion
inflammation
cough
(like common cold)

23
Q

Serious adenovirus symptoms

population

A

Acute respiratory disease

Military recruits

24
Q

Age for respiratory infections from adenovirus

A

under 14

25
Q

Adenovirus significance

A

Frequently used as vector

26
Q

Rhinovirus disease causes

A

upper respiratory infections

27
Q

Rhinovirus incubation period

A

1-4 days

28
Q

Rhinovirus symptoms

A

Red nose
Nasal discharge
epithelial damage

29
Q

Rhinovirus prevention

A

No vaccine

No antivirals

Micro 2 (11 decks)

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