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Micro 2 > L27 Neuroviruses > Flashcards

L27 Neuroviruses Flashcards

1
Q 
Eastern Equine encephalitis
Venezuelan equine encephalitis
Family
Genome
Virion
A

Togaviridae
(+)ssRNA
Enveloped

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2
Q

EEE and VEE require

A

Endoplasmic reticulum

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3
Q

EEE, VEE introduced by

A

bite of infected arthropod

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4
Q

Path to blood stream

A

Langerhans–>lymph node–> blood or

Muscle–>blood

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5
Q

Eastern Equine encephalitis

Incubation period

A

4-10 days

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6
Q

Eastern Equine encephalitis

systemic symptoms

A

chills,fever, malaise, myalgia 1-2 weeks

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7
Q

Eastern Equine encephalitis

Encephalitic disease

A

Fever, headahe, vomit, diarrhea, convulsion, coma

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8
Q

Eastern Equine encephalitis

Encaphalitc disesase death

A

1/3 die within 2-10 days

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9
Q

EEE and VEE

Treatment

A

Vaccine live attenuated TC83

No Treatment

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10
Q

EEE vector

A

Culiseta melanura (excusively feed on birds in freshwater hardwood swamps)

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11
Q

West Nile Virus

Incubation time

A

2-14 days

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12
Q

West Nile Virus

Symptoms

A

Most people are asymptomatic

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13
Q

West Nile Virus treatment

A

No treatment

No vaccine

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14
Q

West Nile mosquitos

A

Culex sp.

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15
Q

Zika virus
Family
Genome
Virion, shape

A

Flaviviridae
(+)ssRNA
Enveloped, spherical

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16
Q

Zika virus host

A

life long infection in mosquitos

17
Q

Zika virus disease

A

Zika fever

18
Q

Zika fever symptoms

A

fever
red eyes
joint pain
rash

19
Q

Zika virus transmission

A

Mosquitos (aedes)
sex
blood transfusion
vertical

20
Q

Zika virus complications

A

Guillain barre syndrom

Newborn microcephaly

21
Q

Why are WNV and EEE so different?

A

Because of their vectors..West nile is all over US

22
Q

Rabies
Family
Genome
Virion

A

Rhabdoviridae
(-)ssRNA
enveloped

23
Q

Rabies virus protein

A

L-polymerase

24
Q

Rabies incubation period

A

1-3 months

25
Q

Rabies spread

A

Locate replication until find neurons

Moves peripheral–>spinal–>brain–>periphery, Salivary glands–>Replication

26
Q

Rabies symptoms

A

Prickling or itching at bite site
Hydrophobia
delirium

27
Q

Rabies survival

A

Once symptoms come, always fatal

28
Q

Rabies treatment

A

Vaccine available
Post exposure vaccine should be administered immediately
Immunoglobulin also

Micro 2 (11 decks)

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