L25 prevention Flashcards

1
Q

types of prevention

A

surveillance

vaccines

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2
Q

types of treatment

A

anti-viral medication
antibodies
interferons

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3
Q

what is in place for surveillance

A

WHO have a global alert and response (GAR) system in place according to:
-international health regulations 2005

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4
Q

what are the international helath regulations 2005

A
notification
verification
assessment 
release of emergency status
advice
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5
Q

what stage of infection do vaccines block

A

attachment

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6
Q

how do vaccines block attachment

A

the bodies produces antibodies against a non-disease causing virion
if infected with virus the antibodies will bind to the receptor binding proteins on the virus stopping attachment

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7
Q

four types of viral vaccines

A

inactivated whole virion
attenuated whole virion
viral mRNA/ whole protein
viral vector with viral gene

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8
Q

describe an inactivated whole virion vaccine

A

dead, main or closely related strain

-heated to 60C or treated with chemicals (formalin)

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9
Q

describe attenuated whole virus vaccines

A

routine culture in unfavourable conditions which causes mutations (loses virulence)

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10
Q

describe a mRNA/whole protein vaccine

A

encapsulated in lipid nanoparticles or complexed adjuvants

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11
Q

describe a viral vector with a viral gene vaccine

A

non-replicating or attenuated viral vector

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12
Q

types of vaccine formulations and doses

A

single (1-3 dose)
combination, different viruses (1-3 doses )
combination, same virus but different types (1 dose)

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13
Q

virus that has a single vaccine

A

chicken pox

covid

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14
Q

virus that has a combination vaccine for different viruses

A

MMR

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15
Q

virus that has a combination vaccine for the same virus but different types

A

influenza

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16
Q

how do antiviral drugs work

A

analogues or inhibitors of crucial steps in the virus life cycle

  • interfere with function of life cycle step or components
  • interrupt life cycle
  • exhibit selective toxicity
17
Q

crucial steps antiviral drugs target

A

entry
genome replication
polyprotein processing
release

18
Q

components that anti-viral drugs target

A

RNA/DNA polymerases
nucleotides/sides
viral proteases

19
Q

which antiviral drug stops HIV envelope-plasma membrane fusion

A

enfuvirtide (fuseon)

20
Q

what anti-viral drug inhibit flu virus nucleocapsid release from endosomes

A

amantadine