L18 Symmetry, genome, shape and size Flashcards

1
Q

what are viruses?

A

acellular microorganisms that require a host to survive

obligate intracellular parasites

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2
Q

aspects of viruses that make them living

A

have self-replicating genome
produce offspring
encode enzymes

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3
Q

what does a viruses ability to encode enzymes do

A

allows it to manipulate the metabolism of the host

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4
Q

what aspects of viruses make it non-living

A

acellular
obligatory dependence on host
do not have their own metabolism

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4
Q

what aspects of viruses make it non-living

A

acellular
obligatory dependence on host
do not have their own metabolism

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5
Q

general structure of a virion

A

nucleocapsid (nucleic acid genome + protein coat)

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6
Q

name of the protein coat

A

capsid

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7
Q

what is the third components that is sometimes present in virions

A

lipid envelope

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8
Q

what is the capsid comprised of

A

multiple units of protein building blocks

-protomers

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9
Q

symmetry of protomers

A

helical
icosahedral
complex

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10
Q

describe a helical structure

A
a helix (spring)
similar to the nucleic acid
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11
Q

example of virus with helical symmetry

A

tobacco mosaic virus

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12
Q

examples of enveloped helical viruses

A

influenza

covid

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13
Q

describe icosahedral symmetry

A

icosahedral (20 face polyhedron)

each face is an equilateral triangle

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14
Q

what happen within each triangular face of viruses with icosahedral symmetry

A

protomers further arrange into units of 5-6 to form capsomers

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15
Q

examples of non-enveloped viruses with icosahedral symmetry

A

poliovirus
adenovirus
papillomavirus

16
Q

examples of enveloped viruses with icosahedral symmetry

A

herpes simplex virus

17
Q

what is binal symmetry

A

when the capsid is separated into two parts;
icosahedral head
helical tail

18
Q

example of a virus with binal symmetry

A

bacteriophage

19
Q

what is complex symmetry

A

when the virus capsid is not either icosahedral or helical

20
Q

example of virus with complex symmetry

A

pox virus

21
Q

structure of pox virus

A

envelope
inner membrane
core with nucleic acid
lateral body

22
Q

components of the viral genome

A

nucleic acid: RNA and DNA

4000->1 million nucleotides

23
Q

possible structures of a virus genome

A

linear
circular
segemented

24
Q

example of a virus with a segmented genome

A

influenza virus

25
Q

example of a virus with a circular genome

A

simian virus

26
Q

example of a virus with a linear genome

A

pox virus, coronavirus

27
Q

4 configurations of the viral genome

A

single-stranded DNA
double-stranded DNA
single-stranded RNA
double-stranded RNA

28
Q

what two configuration are common and which are rare

A

dsDNA and dsRNA common

ssDNA and ssRNA rare

29
Q

example of virus with ssDNA

A

Parvovirus

30
Q

example of virus with dsDNA

A

poxvirus

bacteriophage

31
Q

example of virus with dsRNA

A

influenza

coronavirus

32
Q

example of viruses with ssRNA genome

A

reovirus

33
Q

what is ssRNA divided into

A
positive sense (plus strand)
negative sense (negative strand)
34
Q

example of positive sense ssRNA genome

A

zika virus

corona virus

35
Q

example of negative sense ssRNA viruses

A

influenza

36
Q

shapes of viruses

A
rod
brick 
bullet
filament 
crystal
moon-landing shuttle
crown
37
Q

size range of viruses

A

10nm-400nm

38
Q

what is the largest virus known

A

mimivirus