L21/22 Flashcards

1
Q

sporebearing, lack chlorophyl, have absorptive nutrition and reproduce both sexually and asexually

A

eukaryotic organism

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2
Q

Fungi range from____ forms (yeasts) to____ moulds and mushrooms

A

unicellular
multicellular

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3
Q

Yeasts and moulds

A

microscopic fungi consisting of solitary cells that reproduce by budding. Moulds, in contrast, occur in long filaments known as hyphae, which grow by apical extension

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4
Q

Moulds

A

occur in long filaments known as hyphae, which grow by apical extension

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5
Q

Yeasts

A

are microscopic fungi consisting of solitary cells that reproduce by budding

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6
Q

Heterotrophic fungi

A
  • use reduced, preformed organic molecules as carbon source
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7
Q

Osmotrophic fungi

A

soluble nutrients are absorbed through the cytoplasmic membrane

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8
Q

Saprophytic - fungi

A

derive nutrition from degradation of dead organic matter

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9
Q

Dimorphic – fungi

A

have two different morphological form

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10
Q

Thermally dimorphic fungus exists in the environment in its hyphal/_____form. In the host, the change in temperature induces changes and switch to____-phase

A

mycelial
yeast

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11
Q

Dimorphic fungal pathogens are a significant cause of human disease worldwide and are known as primary_____ pathogens that cause disease in immunocompetent individuals with over 650 000 new infections occurring each year in the United States.

A

pulmonary

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12
Q

Human fungal infections

A
  • 300 known for humans
  • Superficial, cutaneous and subcutaneous mycosis are direct contact infections of the skin, hair and nails.
  • Systemic mycosis - disseminate to visceral tissue
  • Opportunistic mycosis - fungi with low virulence affect immunosuppressed
  • Cause hypersensitivities and poisoning.
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13
Q

Superficial, cutaneous and subcutaneous mycoses are transmitted by___ contact

A

direct

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14
Q

dermatophytes and ringworm

A

The fungi involved in superficial and cutaneous mycosis are also known as this.
* disease known as tinea or ringworm

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15
Q
  • Category for mycoses
    *Scalp, beard, nack, face and arms
  • Piedras and tineas
A

Superficial mycoses

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16
Q
  • Category for mycoses
  • Hair of beard, scalp, skin, buttocks, feet, nails
  • Dermatomycoses (ringworm and tineas)
A

Cutaneous mycoses

17
Q
  • Category for mycoses
  • legs, feet, puncture wounds
  • Sporotrichosis
A

Subcutaneous mycoses

18
Q

The skin is composed of two distinct layers: the

A

epidermis - outermost
and dermis.

19
Q

The outermost layer (the epidermis) is composed of layers of differentiated____. The top layer, or ______ ____, is composed of terminally differentiated, enucleated keratinocytes that are chemically crosslinked to fortify the_____ of the skin

A

keratinocytes
stratum corneum
barrier

20
Q

Superficial mycoses

A

▪ invade only the stratum corneum and the superficial layers of the skin
▪ Dead tissue is invaded and there is no cellular response from the host
Malassezia furfur cause tinea versicolor brownish-red scales on skin of trunk, neck, face, arms
▪ Trichosporon ssp. cause white Piedra, a superficial cosmetic fungal infection of the hair shaft

21
Q

Malassezia furfur

A

cause tinea versicolor brownish-red scales on skin of trunk, neck, face, arms
superficial mycoses

22
Q

Trichosporon ssp.

A

cause white Piedra, a superficial cosmetic fungal infection of the hair shaft
superficial mycoses

23
Q

Cutaneous mycoses

A

▪ Infections of skin cells - require keratin as carbon source for growth
▪ Most com fungal diseases- humans
▪ Common genera of dermatophytes are **Microsporum and Trichophyton **
▪ Tinea corporis

24
Q

ringworm of the body - circular red itchy lesions

A

▪ Tinea pedis
Cutaneous mycoses

25
Q

athlete’s foot - scaling, fissuring, itchy lesions

A

▪ Tinea unguinum
Cutaneous mycoses

26
Q

nail infection - nail discoloured, separates from nail bed

A

▪ Tinea cruris
Cutaneous mycoses

27
Q

Jock itch - proximal medial thighs, genital, pubic, perineal, and
perianal skin

A

Cutaneous mycoses

28
Q

Tinea is transmitted via the

A
  • feet by desquamated skin scales in substrates like carpet and matting.
  • Desquamated skin scales may remain infectious in the environment for months or years
29
Q

Subcutaneous mycoses

A

▪ Caused by dermatophytes that infect under the skin
▪ Fungi normally saprophytic inhabitants of soil and decaying vegetation
▪ Introduced via puncture wound
▪ Disease develops slowly, often over years

30
Q

Osmotrophic microorganisms feed by secreting extracellular ____into the environment to degrade complex polymers, such as cellulose, lignin and proteins and by transporting the resulting simple, monomeric sugars and amino acids into their own cells.

A

depolymerizing enzymes

31
Q

Subcutaneous mycoses - Sporotrichosis caused by

A

Sporothrix schenckii, a dimorphic fungus (filamentous form in environment, yeast form in host)

32
Q

Subcutaneous mycoses - Sporotrichosis information

A

▪ Caused by Sporothrix schenckii
▪ Occurs worldwide, most common in USA
▪ Found on plants – roses, hay, pine bark mulch etc.
▪ Disease is occupational hazard for florists, forestry workers
▪ Secondary spread to articular surfaces, bone and muscle is not infrequent,. Infection occasionally involve the central nervous system, lungs or genitourinary tract.

33
Q

Systemic mycosis

A

▪ acquired by an air-borne route when spores are inhaled from the soil where the free-living fungi are found
▪ Caused by thermally dimorphic fungi: Coccidioides, Histoplasma, Blastomyces, Paracoccidioides, Emmonsia, and Emergomyces

34
Q

Systemic mycosis caused by thermally dimorphic fungi:

A
  • Coccidioides,
  • Histoplasma,
  • Blastomyces,
  • Paracoccidioides,
  • Emmonsia, and
  • Emergomyces
35
Q

Coccidioidomycosis

A

▪ Valley fever, San Joaquin fever, desert rheumatism
▪ Coccidioides (C.) immitis and Coccidioides posadasii
▪ C. immitis, primarily endemic in California, and C. posadasii, endemic elsewhere throughout the Western Hemisphere.

36
Q
A