L1 Host and parasite relationship intro Flashcards
What is Infectious Disease?
an infectious disease is any change from a state of health in which part or all of the host’s body cannot carry on its normal functions because of the presence of an infectious agent or its products
Explain how an infectious disease is like a battle
the host provides protection, nutrients and energy
pathogen must:
access and exploit the host
access new hosts
the host must resist infection
Parasitism
symbiotic interaction between two organisms in which one benefits at the expense of the other
Parasites characteristics
- live on or within a host organism
- use the host to achieve metabolism (‘dependence’)
- parasite benefits from the association
- host is usually harmed
- typically cause disease in the host
- the term includes bacteria, viruses, fungi, protists
Microbiome in human features
protective function, development and maturation of the immune system, regulatory function of the nervous system, metabolic and nutritional function.
Microbiota dysbiosis
lead to dysregulation of bodily functions and diseases including cardiovascular diseases, cancers, respiratory diseases, etc.
Infection
the parasite grows and multiplies in or on its host
Infectious disease (an outcome)
where infection detrimentally affects host function
Pathogen
any organism causing infectious disease
Types of pathogens
Primary and opportunistic
Primary pathogens -
cause infectious disease in healthy hosts
Opportunistic pathogens -
cause infectious disease in ‘compromised’ hosts, e.g., immunocompromised or
wounded hosts; may be part of the normal microbiota (normal flora)
Pathogenicity
the ability to cause disease
Virulence
the degree or intensity of pathogenicity e.g., indicated by fatality rate or ability to damage host tissues
What does it mean when some pathogens can enter a latent state
The pathogen is present, but no symptoms are evident (chicken pox/varicella)
The infectious Disease Process
- Incubation period
- Prodromal stage
- Illness period
- Convalescent period (or death)
Infection process: Incubation period
- Time from pathogen entry to development and the signs and symptoms (little to none)
- Pathogen development but no clinical manifestations