L2 Flashcards

1
Q

Gametogenesis is characterized by four stages what are they

A

1- Origin and migration
2-proliferation by mitosis
3-reduction by meiosis
4- maturation

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2
Q

An increase in the number of germ cells by mitosis ensures that

A

A large preserver of future gametes

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3
Q

Which phase of gametogenesis is identical in males and females

A

Origin and immigration

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4
Q

Error in phase 1 can lead to

A

Phase 1 is origin and immigration, incorrect migration of germ cells lead to congenital anomalies/teratomas

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5
Q

Genes on the same chromosomes are known as

A

Linked genes

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6
Q

True or false: the pattern of my mitotic division of germ cells differ from males and females germ cells

A

True

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7
Q

Replication occurs in which stage

A

 interphase

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8
Q

Mention three events of prophase

A

Chromosome condensation
centromere development
nucleus breaks

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9
Q

Mention the events of metaphase

A

Further condensation
Centrosomes are at the opposite sides
alignment

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10
Q

Mention the events of telophase

A

Nucleus reforms
Decondensation 

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11
Q

The first division in meiosis separates

A

Homologous chromosomes

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12
Q

The second division in meiosis separates

A

Sister chromatids

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13
Q

How many chromosomes are there after the first division in meiosis

A

23

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14
Q

Genetic variation is a result of ____ in the ___ stage

A

Crossing over ophthalmologist chromosomes and random distribution

Meiosis one

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15
Q

A primary germ cells give

A

Males :
22+x
22+x
22+y
22+y
All mature

Females
22+x (mature)
22+x ( atresia)
22+x ( atresia)
22+x ( atresia)

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16
Q

The number of germ cells in female peaks in__ due to

A

Between the second and fifth month
Do you to mitosis

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17
Q

Spermatogonia maintain the ability to divide throughout

A

Postnatal life

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18
Q

Prepubertal stage: mostly
[Follicular pool/ atretic follicles/ growing follicles/ovulated follicles]

A

1:follicular pool
2: Atretic pool

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19
Q

Adult stage: mostly
[Follicular pool/ atretic follicles/ growing follicles/ovulated follicles]

A

1: follicular
2:atretic
3: growing
4: ovulated

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20
Q

Post menopausal stage: mostly
[Follicular pool/ atretic follicles/ growing follicles/ovulated follicles]
ادري انج حافظتهم بالترتيب فحفظي fago

A

1:atretic
2: ovulated

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21
Q

Cells from mitosis plus a flat epithelium gives

A

Primordial follicle

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22
Q

How many polar body one and polar body two does a female produce

A

2 polar body I
1 polar body II

23
Q

By the end of ____ the oogonia underwent a number of my mitotic division and are arranged in clusters surrounded by a layer of flat epithelium

24
Q

At birth, the primary oocyte have started prophase of meiosis one but they donot enter metaphase until ___ but rather they are in __

A

Puberty
Diplotene stage

25
Most oocytes become atretic during __
Childhood
26
___# are present by puberty ___#will be ovulated
40,000 <500
27
At puberty, pool of growing follicles are established from __
Primordial follicles
28
Each month # to # are selected from the pool and begin to mature and pass through three stages __ __ __
15-20 Primary, preantral Secondary, antral Preovulatory (graafian follicle)
29
When do the surrounding follicle cells change from flat to cubodial and why?
As the primary oocyte begins to grow To produce stratified epithelium of granulosa cells
30
What are the three stratified epithelium of the granulosa sense
Corona radiata zona pellucida Theca folliculi
31
After the first meiotic division # follicle Is produced 
Secondary follicle
32
After the second meiotic division # follicle is produced
Tertiary
33
Meiosis in males begin at __while in females__
After puberty At birth
34
What is the difference between type a and type B Spermatogonium
Type A: primordial cell, before migration Type B: after migration, DNA replication
35
In what type of germ cells all primary cells enter meiosis at the same time
Female gametes
36
What is the result when is primary spermatogonium enters the meiotic phase as a primary spermatocyte and how long does it take
2 secondary spermatocytes, which enter the second meiotic division and result in four haploid spermatids >>> Spermiogenesis>> Mature sperm 64 days
37
Mention four events of the maturation of sperms
Formation of the acrosomal which covers half of the nuclear surface Condensation of the nucleus Formation of the neck, middle piece, tail Shedding off most of the cytoplasm as residual bodies. 
38
Mention six symptoms of down syndrome
Mental retardation delayed growth premature aging distinct facial characteristics intellectual disabilities thyroid dysfunction infections
39
Mention four symptoms of trisomy 13
Mental retardation deafness Eyedefects cleft lips
40
Mention four symptoms of trisomy 18
Mental retardation congenital heart defects Low set of ears flexion of fingers and hands
41
What is the origin of primordial germ cells
Extra embryonic yolk sac
42
To where the priomordial germ cells migrate to
Gonads 
43
Accumulation of unwanted PGC in areas that they’re not supposed to be results in
Teratomas
44
Proliferation by mitosis differs in males and females because it is slower in __ but have a higher rate in __ In __ they are life long but in __ they stop at birth
Males females males females
45
When does Spermatogonium becomes a primary spermatocyte
At puberty
46
Why are follicles important? 
For the oocyte to become ready for fertilization, because follicles provide nutrients to the oocyte
47
When does the oogonia undergo Artesia
5 months - Premenopuase
48
In the fetal period __ #follicles are present
0
49
When do the flat cells change to cuboidal and why
As the primary oocyte grows , To produce stratified epithelium of granulosa cells which are zona pellucida - corona radiata - theca folliculi
50
What is the origin of primordial germ cells What is the constituent of primordial germ cells
A: extraembrionic yolk sac B: clusters from meiosis +flat epithelial cells
51
When does the oogonia undergo atresia Most oocytes become atretic during
5 months - premenopausal Childhood
52
Clusters of cells + flat epithelial cells are in the __month
3rd
53
When does the # of 1* oocyte decrease
Midgestation