L10 Active Learning Questions

Question 1

Which of these statements regarding the Na+/k- ATPase pump is correct?
A. Activity of the Na+-K+ ATPase pump is driven by the addition of a phosphate group to ADP.
B. It does not become saturated.
C. It helps to maintain high intracellular K+ concentrations.
D. It mediates passive transport.
E. It moves both Na+and K+ down their electrochemical gradients.

Answer 1

C. It helps to maintain high intracellular K+ concentrations

Question 2

From the following properties, name the receptor described. 1. Once activated it brings about a response within milliseconds. 2. It has a permeation pathway for cations. 3. It is expressed by post-ganglionic neurons of the ANS and skeletal muscles.
A. Beta adrenergic receptor
B. GABAA receptor
C. Histamine receptor
D. M2 receptor
E. Nicotinic ACh receptor

Answer 2

E. Nicotinic ACh receptor

Question 3

Which of the following does NOT happen in response to an increase in sympathetic nervous system activity?
A. Constriction of airways.
B. Increase in heart rate.
C. Increased glucose production in the liver.
D. Increased secretion of adrenaline from the adrenal medulla.
E. Pupils dilate.

Answer 3

A. Constriction of airways

Question 4

Which statement about an active G protein is correct?

A. AGTP molecule is bound to the beta subunit
B. Only alpha subunits can bind to proteins to bring about a response
C. The 3 subunits of a G protein remain associated
D. They are free to move around in the cytosol
E. They dissociate from the G protein coupled receptor

Answer 4

E. They dissociate from the G protein coupled receptor

Question 5

An M2 agonist would:
A. activate a Gαs protein on ventricular myocytes.
B. depolarise cardiac pacemaker cells.
C. increase heart rate.
D. increase K+ channel opening in sinoatrial node cells.
E. increase ventricular myocyte contraction.

Answer 5

D. Increase K+ channel opening in sinoatrial node cells

Question 6

Sarin is an acetylcholinesterase inhibitor. What effects could inhalation of Sarin cause?

A. Bronchodilation.
B. Excessive mucus secretion.
C. Excessive pupillary dilation.
D. Inability to urinate.
E. Relaxation of skeletal muscles.

Answer 6

B. Excessive mucus secretion.

Question 7

Which of these is NOT a common drug target?
A. Receptors
B. Second messengers
C. Ion channels
D. Transporters
E. Enzymes

Answer 7

B. Second messengers