L-2 Basics of disease Flashcards
disease results from alterations in….
- structure or amount
- biochemical reactions and processes
monosaccharide
glucose
fructose
galactose
disaccharides
sucrose (glucose & fructose)
lactose (glucose & galactose)
polysaccharides
muscle glycogen
starch
cellulose
lactose intolerence
what enzyme breaks lactose
what happens to unabsorbed lactose
- lactose must be digested into monosaccharides before it can absorbed in intestine
- lactase enzyme breaks lactose
- unabsorbed lactose causes gas, cramping and diarrhoea
Galactosaemia
Its an inherited disorder
Its the inability to metabolise galactose which causes accumulation galactose-1-phosphate in blood
If infant with galactosaemia gets milk they get
- liver damage
- cognitive development delay
- kidney failure
physical agents cause major disease
- change in temperature/climate
- radiation
chemical agents & drugs cause disease
- Toxic compounds
- certain drugs
Biologic agents causes disease
-viruses
-bacteria, fungi, higher parasites, prions
Lack of oxygen cause disease
-loss of blood
-ischemic heart disease
genetic causes disease
-germline mutation (inherited mutation)
-somatic mutation (not inherited)
immunologic reaction cause disease
-autoimmune (failure of self recognition by body)
-analaphylaxis (extreme allergy)
nutritional imbalance cause disease
-nutrient deficiencies
-nutrient excesses
endocrine imbalance cause disease
-hormone deficiencies
-hormone excesses
what’s antigenic variation
Pathogens are able to change expression and prevent recognition.
Human viruses can exchange genes with the viruses of domestic animals