Kalıtım materyali olarak DNA Flashcards
Genetic material must show 4 traits
Replication
Genetic information storage
Expressing stored genetic information
variation
What is griffiths experiment
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Whatiç Avery, Macleod an Mccarry experiment
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What is hershey and chase experiment
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What did Erwin Chargaft and his colleagues du?
used hromatographic methods to separate four bases
revealed some common features of DNA
Chargaff Rules
Adenin= Thymine
cytosine- guanine
A+T/ C+G = ucries by species this ratio is different in different Organisms; but it is the same in different tissues of the some organisms
complementary base pairing
T+C =A+G
Rosalind Franklin
X_ray dffraction photograph of pure DNA strands in form B
showed that the molecule was helical
Watson and Crick
right handed double helix structure
the two chains are opposite each other
3.4Å between the bases
only A-T G-C pairing are possible
full turn of the helix is 34Å, 10 bases per turn
major grooves minor grooves
the diameter of the helix is 20Å