Jaundice Flashcards
What are the three types of jaundice?
Pre-hepatic
Hepatic
Post-hepatic
What is the LFT picture in pre-hepatic jaundice?
Raised unconjugated bilirubin
Why does pre-hepatic jaundice occur?
Breakdown of RBCs
What causes of pre-hepatic jaundice?
Haemolytics anaemias
Sickle cell
Thalassaemia
DIC
What is the LFT picture in hepatic jaundice?
Raised bilirubin
Raised ALT
Raised AST
Why does hepatic jaundice occur?
Liver damage
What causes hepatic jaundice?
Hepatitis Gilbert's syndrome Alcohol Drugs Malignancy
What is the LFT pattern in viral hepatitis?
ALT>AST
What is the LFT pattern in alcoholic hepatitis?
AST>ALT
What is the LFT picture in post-hepatic jaundice?
Raised conjugated bilirubin
Raised ALP
Raised GGT
Why does post-hepatic jaundice?
Bile blockage
What causes post-hepatic jaundice?
Gallstones
Malignancy
Biliary strictures