Dyspepsia Flashcards
What is dyspepsia?
Term to describe discomfort in the upper GI tract
What are common symptoms of dyspepsia?
Heartburn
Reflux
Indigestion
What can cause dyspepsia?
Malignancy Non-ulcer disease Ulcers GORD Gastritis
What are red flag symptoms?
>55 Anorexia Loss of weight Anaemia Recent onset of progressive symptoms Malaena / haematemesis Swallowing difficulties
What do you do if there are any red flag symptoms?
2 week wait referral for endoscopy
How do you manage new onset dyspepsia?
- Stop NSAIDs
- Simple antacids
- Test for H.pylori - eradicate
- PPI
What is H.pylori?
Helicobacter pylori - gram negative helix shape bacteria
What is the effect of H.pylori?
Produces urease – converts urea to ammonium – increases pH - damages gastric mucosa
How do you investigate H.pylori?
Carbon-13 urea breath test
Stool antigen test
How do you treat H.pylori?
Omeprazole
Clarithromycin
Amoxicillin
What is the mnemonic for red flag symptoms of dyspepsia?
> 55
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