Hepatorenal Syndrome Flashcards
1
Q
What is hepatorenal syndrome?
A
Detioration in kidney function in those with liver disease
2
Q
What is the pathophysiology of hepatorenal syndrome?
A
Vasoactive mediators cause splanchic vasodilation - reduces systemic vascular resistance
Triggers RAAS - causing renal vasoconstriction
3
Q
What are the types of hepatorenal syndrome?
A
Type 1
Type 2
4
Q
What are the features of type 1?
A
Rapidly progressive
Doubling of serum creatinine in less than 2 weeks
Very poor prognosis
5
Q
What are the features of type 2?
A
Slowly progressive
6
Q
How is hepatorenal syndrome managed?
A
Terlipressin
Transjugular intrahepatic portosystemic shunt
