Gilbert's Syndrome Flashcards
1
Q
What is Gilbert’s syndrome?
A
Condition of defective bilirubin conjugation
2
Q
What is the inheritance pattern of Gilbert’s syndrome?
A
Autosomal recessive
3
Q
What is the pathophysiology of Gilbert’s syndrome?
A
Deficiecy of UDP glucurosyltransferase leads to decreased conjugation of bilirubin
4
Q
What are risk factors for Gilbert’s syndrome?
A
Post puberty
FHx
5
Q
What are the features of Gilbert’s syndrome?
A
Jaundice
- when under physical or psychological stress
6
Q
What investigations are done for suspected Gilbert’s syndrome?
A
Bloods
- LFTs
7
Q
What will the LFTs show in Gilbert’s disease?
A
High unconjugated bilirubin
8
Q
How is Gilbert’s syndrome managed?
A
Reassurance
Avoid stress
