Iron Deficiency Anemia Flashcards
What causes iron deficiency anemia?
Insufficient iron available for erythropoiesis resulting in anemia.
What is the most common type of anemia throughout the world?
Iron deficiency anemia
Etiology of IDA
- Chronic blood loss (i.e Chron’s disease, etc.)
- Inadequate dietary intake of iron
- Medications: GI meds, NSAIDs..
- Surgical Procedures (any procedure that predisposes the patient to bleeding)
- Medical Conditions (i.e ulcerative colitis, kidney failure)
- Eating disorders (pica)
- Pregnancy
- Blood donation
Etiology for IDA that is common in females
Menorrhagia
Etiology for IDA that is common in males
Ulcers, hemorrhoids, cancer
How can pregnancy cause IDA?
D/t high requirement of iron because of the fetus
IDA is common in
Adolescents, children (<2 y.o.)
Iron
Is in constant use in the body and can be “recycled”
Iron is stored in the form of
Hemoglobin
IDA develops
Slowly and overlapping 3 stages
Iron Deficiency Anemia: Stage I
Body’s iron stores for red cell production and hemoglobin synthesis are depleted.
Iron Deficiency Anemia: Stage II
Insufficient amounts of iron are transported to the marrow and THEN iron deficient red cells are produced (impaired erythropoiesis)
Iron Deficiency Anemia: Stage III
Insufficient iron supply & diminished HGB synthesis (clinical manifestations appear in this stage)
Normal Plasma Ferritin
60
Normal Transferrin Saturation (%)
35