Antibiotics: Part 2 (Based off of PowerPoint only) Flashcards
Aminoglycosides include
Amikacin Gentamicin Neomycin Streptomycin Tobramycin
Mechanism of Action: Aminoglycosides
- Binds to 30s bacterial ribosomes, inhibit protein synthesis,
- Suppress bacterial growth
Indications for Aminoglycosides
Serious/life threatening infections caused by E.coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa
Contraindications for Aminoglycosides
Allergy to aminoglycosides, renal insufficiency
Adverse Effects of Aminoglycosides
- Ototoxicity
- Nephrotoxicity
- Vertigo, dizziness, headaches, paresthesias
Interactions of Aminoglycosides
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Nursing Process & Patient Centered Care: Patient Teaching (pp. 634-638) for Aminoglycosides
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Quinolones include
Ciprofloxacin Levofloxacin Moxifloxacin Gemifloxacin Ofloxacin Norfloxacin
Mechanism of Action: Quinolones
- Inhibits DNA gyrase (enzyme required for synthesis of bacterial DNA)
- Bactericidal
Indications for Quinolones
- Most quinolones are used for moderate to serious infections of the respiratory tract, bones, skin, GI, GU (genitourinary), septicemia
- Box 39-2 outlines the susceptible organisms
Contraindications for Quinolones
Allergy to Quinolones
Adverse Effects of Quinolones
Refer to Table 39-3, p. 629
Interactions of Quinolones
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Nursing Process & Patient Centered Care: Patient Teaching (pp. 634-638) for Quinolones
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Clindamycin includes
Clindamycin, Cleocin
Mechanism of Action: Clindamycin
- Inhibits protein synthesis
- Bacteriostatic
- Bactericidal (high concentration)
Indications for Clindamycin
Moderate to serious infections of the respiratory tract, bones, skin, GI, GU (genitourinary), septicemia