IR and Palliation Flashcards

1
Q

Antegrade pyelography

A
  • Renal pelvs punctured under US guidance, radiographic contrast medium injected to demonstrate anatomy and level of obstruction
  • Urine can also be aspirated for microbiology/cytology
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2
Q

Percutaneous nephrostomy

A
  • Insertion of a pigtail catheter into the collecting system

- External bag for short term drainage, otherwise internal stenting generally preferred

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3
Q

Biliary drainage

A

ERCP with stent

  • stents inserted endoscopically, if at the low CBD
  • Failure rate 30-40% plastic stents, 10-15% with metallic
  • Higher rates of cholangitis with plastic stents
  • If stents occlude, can be replaced (plastic) or have patency restored (metallic)
  • Generally worthwhile for QOL improvement unless life expectency is very short

Percutaneous transhepatic biliary drainage

  • Used if level of biliary obstruction is high (proximal to common bile duct) or there is distorted anatomy (prev surgery, local tumour)
  • Also second line if ERCP fails
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4
Q

Thoracentesis

A
  • Indicated at first presentation of a pleural effusion for diagnosis and therapeutic purposes
  • Typically done with US
  • Fluid re-accumulates in almost all patients, at which point decision is for pleurodesis vs a tunneled pleural catheter
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5
Q

Tunnelled pleural catheter

A
  • Useful for patients who are ineligible for chemical pleurodesis or those who fail
  • Soft catheter with polyester cuff to promote fibrosis to the subcutaneous tissue
  • Drainage every other day
  • Spontaneous pleurodesis occurs in up to 70% of patients
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6
Q

Chemical pleurodesis

A
  • Ultrasound guided insertion of a tube thoracostomy
  • Infusion of sclerosing agent (doxycycline, talc, bleomycin)
  • May be painful for some patients
  • Tunnelled pleural catheters now preferred in some centres
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7
Q

Indwelling pleural catheter

A
  • Alternative to repeated paracentesis
  • Use of tunnelled drain catheter with complication rate similar to that for large volume paracentesis, with drainage facilitated at home
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8
Q

Esophageal stents

A
  • Self-expanding metal stents commonly used for dysphagia
  • Placement can be done with fluoroscopy or endoscopy
  • Low complication rate
  • Covered metallic stents also useful for malignant esophageal fistulas to provide a seal, allow normal PO intake, and prevent thoracic sepsis/malnutrition
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9
Q

Gastroduodenal stents

A
  • Nonsurgical alternative to treating GOO, particularly in patients who may be too frail for a surgical intervention
  • Most appropriate for patients with a lifespan of 2-6 months
  • Goal is for resumption of PO intake without obstructive symptoms and improved QOL
  • Less likely to be successful when obstruction is due to peritoneal carcinomatosis
  • May also be a temporising measure to allow stabilization of the patient prior to definitive surgery
  • Note that covered stents are more likely to result in perforation - use only uncovered
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10
Q

Colorectal stents

A
  • Self expanding metal stents

Indications:

  • Palliation of surgically incurable colorectal cancer
  • Emergent bridge to surgery, allowing for optimization and pre op staging
  • Management of some patients with extracolonic pelvic tumours (e.g. ovarian ca)

Contraindications:

  • Systemic toxicity (e.g. colonic ischemia)
  • Intra abdominal abscess
  • Persistent coagulopathy despite treatment
  • Treatment with bevacizumab (high perforation rates)

**Avoid in distal rectal lesions (within 5 cm of anal verge) as a stent can induce pain, tenesmus, and rectal bleeding - but may allow patients to avoid an ostomy and some patients may wish to try it

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11
Q

Tracheobronchial stents

A
  • Self expanding metallic stent for malignant airway obstruction
  • Under general anesthesia, with IR and bronchoscopist
  • Bronchoscopy to visualise stricture, marked with a radio-opaque marker, then dilatation under fluoroscopic guidance followed by insertion of a SEMS

Goal

  • Symptomatic improvement
  • Prevent collapse or infection/abscess beyond an obstruction lesion

**Consider a plastic covered metallic stent for a trachoesophageal fistula where esophageal stent is not feasible

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12
Q

Intravenous thrombolysis for SVC syndrome

A
  • Superior venocavography to visualise site and extent of obstruction
  • Can also be used for IVC obstruction
  • Simple procedure that can improve WOL

Procedure:

  • General anesthetic and selective thrombolysis if there is extensive thrombosis
  • Percutaneous transfemoral dilatation of the narrowed SVC, followed by insertion of a self expandable metallic stent
  • If tumour is compromising the trachea, airway stent can be placed during procedure as well
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13
Q

Insertion of an IVC filter

A

Indications
- VTE with absolute contraindication to therapeutic anticoags (ICH, severe active bleeding, recent brain/eye/spinal cord surgery, pregnancy, malignant hypertension), complications of coags, or failure of anticoag where there is acute proximal venous thrombosis

Controversy
- Retrospective study concluded higher 30 day mortality with ICV filter placement

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14
Q

Percutaneous gastrostomy

A
  • Useful when patients are receiving feeds and patients wishes to avoid NG tubes or will require feeds long term
  • Placed under fluoroscopy or endoscopic guidance and local anesthesia

Gastrostomy tubes preferred, but gastro-jejunostomy tubes are preferable if there is GOO or GERD

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15
Q

Extraction of ‘lost’ indwelling venous cannulas or catheters

A
  • Equipment may break or dislodge with the catheter (or part thereof) ‘lost’ in the venous system
  • Must be retrieved so that they do not perforate vascular structures, cause dysrhythmias, or cause infection

Technique

  • Typically lodge in the right side of the heart or pulmonary arteries
  • Typically removed with fluoroscopic guidance
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16
Q

Palliative embolization

A
  • Used to control pain, hemorrhage, and hormone production while also reducing tumour bulk
  • In some cases, embolization of tumours may improve survival
  • Includes ‘TACE’ - transcatheter arterial chemo-embolization’ (cytotoxic agents mixed with embolic materials), used with HCC
  • Requires attention to pre-medication (antibiotics to prevent infection, blockade for hormonal tumours, etc.)
17
Q

Post-embolization syndrome

A
  • Discomfort, pain, fever, and elevated WBC for a few days following embolization of large tumour masses
  • Typically due to the presence of necrotic tissue
  • Sustained pyrexia is concerning for abscess formation (get blood cultures and US or CT to image)
18
Q

RFA of HCC/hepatic mets

A
  • Alternating current to induce ionic agitation, frictional heat production within the tissues and cell death
  • Generally tolerated well

Complications

  • Transient elevation of liver enzymes
  • Abscess formation
  • Intraperitoneal hemorrhage

Monitoring

  • CT to gauge remaining viable tumour (US not very helpful as fibrotic and neoplastic lesions look similar)
  • Follow AFP or CEA for trend
19
Q

RFA of renal masses

A
  • Useful for patients who are poor candidates (though nephrectomy - complete or partial - is standard of care)
  • May also be helpful for persistent hematuria
  • Preserves kidney function
  • Centrally located masses in the kidney harder to treat

Complications:

  • Hemorrhage
  • Urinoma
  • Abscess
  • Paresthesias
  • Transient hematuria
  • Pain
20
Q

RFA of adrenal tumours

A
  • RFA may improve survival in patients who are not able to undergo surgical excision
  • Ensure appropriate endocrine evaluation is complete with appropriate blockade prior to treatment
21
Q

RFA of lung tumours

A
  • Useful when palliation for pain or a mass lesion is needed or for patients with a small primary NSCLC who are not operative candidates due to comorbidities

Complications:

  • Pneumothorax (10-20%)
  • Bleeding
  • Fistula
  • Hemoptysis
  • Effusions
  • Fever
  • Infection
  • Pain
22
Q

RFA of soft tissue mets

A
  • May be useful for painful soft tissue tumours resistant to conventional rads or pharm therapies
  • Short term local control