Introduction to Cell structure Flashcards

1
Q

The external boundary that serves as a barrier, controlling entry and exit of substances

-The site of communication between cells and their environments

A

Plasma membrane (PM)

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2
Q

Segregates the internal structure of the nucleus from the cytoplasm

A

Nuclear Envelope

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3
Q

Cells that secrete peptides and proteins have extensive

-A membranse structure to which ribosomes are attatched

A

Rough ER’s

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4
Q

What are the two main intracellular compartments?

A

Nucleus and Cytoplasm

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5
Q

The nucleus has a subdomain known as the

A

Nucleolus

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6
Q

The cytoplasm has which two sub domains?

A
  1. ) Membrane bound organelles

2. ) Cytosol

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7
Q

Synthesize and secrete immunoglobulins and have extensive rough endoplasmic reticulums

A

Plasma Cells

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8
Q

Cytoplasm outside of the organelles, containing soluble enzymes, inclusions (glycogen, granules, and lipids), cytoskeletal elements, and free polysomes

A

Cytosol

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9
Q

mRNA + ribosomes

A

Polysomes

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10
Q

What are the three major structural areas of the nucleus?

A

Nuclear Envelope, Nuclear Pore, and Nuclear Lamina

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11
Q

Double membrane that segregates nuclear contents

A

Nuclear envelope

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12
Q

The outer membrane of the nuclear envelope is continuous with the ER and has

A

Ribosomes

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13
Q

The nuclear envelope encloses

A

Chromatin and nucleoplasm

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14
Q

Contains the genetic material of the cell

A

Chromatin

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15
Q

Contains soluble nucleotides and proteins

A

Nucleoplasm

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16
Q

What are the two types of Chromatin?

A

Euchromtin and heterchromatin

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17
Q

Actively transcribed DNA

A

Euchromatin

18
Q

Inactive DNA that is highly condensed and usually near the periphery of the nucleus

A

Heterochromatin

19
Q

The site of ribosomal RNA synthesis and the site of the assembly of ribosomal subunits

20
Q

The ribosomal subunits consist of rRNA and several proteins that were first synthesized in the cytosol and then transported to the

21
Q

A structure composed of pecific intermediate filament proteins (the LAMINS)

A

Nuclear lamina

22
Q

Form a dense felt-like area under the nuclear membrane, which helps maintain nuclear structure

23
Q

Phosphorylation and dephosphorylation of the nuclear lamins regulate the stability of the nuclear envelope during

24
Q

Results in the break down of the nuclear envelope during prophase of mitosis

A

Phosphorylation of lamin B

25
Large complex structures (30 different proteins) organized with octogonal symmetry that transport macro- and micromolecular structures in and out of the nucleus
Nuclear Pores
26
Leave the nucleus through the nuclear pore
Molecules involved in protein synthesis (mRNA, tRNA, ribonucleoproteins)
27
Made in the cytoplasm fro mRNA and enter the nucleus through the nuclear pore
Proteins used in gene regulation (histones, polymerases, etc)
28
Contains the cytoskeleton (which forms the structural framework of the cell), cytoplasmic inclusions, soluble enzymes/ions, and free polysomes
Cytosol
29
What are three special types of proteins contained in the cytosol?
Actin, Tubulin, Intermediate filaments
30
Contain filaments called microfilaments
Actin
31
Contain structures called microtubules
Tubulin
32
Similar to nuclear lamins
Intermediate filaments
33
Metabolic products such as lipids (in the form of lipid droplets) and glycogen (polymer of glucose), are not enclosed by a cell membrane and are stored in the cytosol as
"inclusions"
34
The cytosol contains numerous soluble proteins and enzymes involved in
Intermediate Metabolism
35
Particles composed of rRNA and Multiple proteins that are assembled as large and small subunits
Ribosomes
36
The large and small subunits of ribosomes combine with mRNA to promote
Translation
37
Ribosomes attached to the ER will produce proteins that enter the
Secretory pathway
38
In the cytosol, free polysomes synthesize specific proteins that are used
Within the cell (not secreted)
39
Importantly, nuclear proteins that regulate replication and gene expression, such as DNA polymerases and transcription factors, as well as proteins of the ribosome itself, are made on
Free ribosomes
40
Ribosomal proteins made in the cytoplasm associate with rRNA produced in the
Nucleolus